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Automatic prediction of cotton leaf's diseases using deep learning techniques

Cotton leaf diseases present a major threat to global cotton production, significantly impacting both yield and fiber quality. Traditional diagnostic methods are labor-intensive, time-consuming, and demand highly skilled professionals, making them inefficient for large-scale agricultural applications. Although earlier deep learning -based approaches have shown promising results in identifying cotton leaf diseases such as Bacterial Blight, Fusarium Wilt, and Curl Virus Disease, their performance...

Jul 5, 2026Read Abstract →

Menopause and comorbidity assessment in cisgender women living with HIV in Victoria: A clinic record review of women seen at three tertiary centres in Melbourne, Australia

CONCLUSION: Approximately half the women in this study were aged 40-56 years, yet menopausal status was unable to be determined for over a quarter of the cohort. Documentation of menstrual or menopausal symptoms was poor and significant gaps were identified in comorbidity screening. Further research is needed to understand the impact of menopause on women living with HIV in Australia. Clinical guidelines need updating to include gender-specific health needs of women living with HIV and to...

Jul 5, 2026Read Abstract →

Clinico‑pathological profile of oral squamous cell carcinoma: a five‑year analysis of 150 cases at Alexandria University

CONCLUSION: American Joint Committee on Cancer 8th edition staging demonstrated improved risk stratification and stronger associations with recurrence and survival outcomes compared to traditional TNM staging in Oral Squamous Cell Carcinoma patients. Depth of invasion, extranodal extension, and the combined histopathological risk pattern were strongly associated with aggressive tumor behavior and poorer outcomes. These findings provide valuable data from an Egyptian and Middle Eastern population...

Jul 4, 2026Read Abstract →

Health Policy and Value Assessment Through the Health Equity Lens: How Far from Being Incorporated Routinely? An Environmental Scan of Frameworks and Policy Gaps

CONCLUSIONS: Existing frameworks identified in this environmental scan promote the expansion of value elements in technologies' assessment and provide structured guidance on the study design and outline the analytical capabilities and technical elements required to allow routine incorporation of health equity in decision making.

Jul 4, 2026Read Abstract →

Immune evasion, infectivity, and membrane fusion of SARS-CoV-2 variants LP.8.1.1, XEC.25.1, XFG, and NB.1.8.1

Emerging SARS-CoV-2 variants, with potentially enhanced immune evasion and transmissibility, pose a serious challenge to public health. This study provides a systematic characterization of the virological features of JN.1 descendant subvariants, including LP.8.1.1, KP.3, XEC.25.1, XFG, and NB.1.8.1, focusing on their infectivity, receptor binding, membrane fusion, and immune evasion capacity. Multiple JN.1 descendant variants exhibited reduced infectivity across various human cell lines, whereas...

Jul 4, 2026Read Abstract →

Evaluating current bronchiectasis care in Italy according to the 2025 European respiratory society recommendations

CONCLUSION: Despite clear progress, substantial variability persists in physiotherapy access, rare disease diagnostics, self-management tools, and routine monitoring. Updated Italian quality standards aligned with ERS 2025 principles are warranted.

Jul 4, 2026Read Abstract →

Emerging artificial intelligence advances in oncology: latest updates from the 2026 AACR annual meeting

Advances presented at the 2026 American Association for Cancer Research (AACR) Annual Meeting highlight a shift from standalone artificial intelligence (AI) models to integrated, agentic systems across oncology. Platforms such as Synapse enable large-scale data coordination, supporting interoperable and reproducible research. Building on this foundation, conversational and multi-agent AI tools (e.g., DrBioRight, GP CoPilot, Isabl AI Agent) allow natural language interaction with multimodal...

Jul 4, 2026Read Abstract →

Testing for Non-Severe Heritable Platelet Function Disorders

Heritable platelet function disorders (HPFD) are a diverse group of bleeding disorders characterised by a primary qualitative defect in platelet function rather than platelet number. HPFD may be broadly categorised according to the severity of bleeding, with Glanzmann thrombasthenia and Bernard Soulier syndrome classically considered severe HPFD, with well-described clinical and laboratory phenotypes. The remaining non-severe HPFD are less completely characterised and provide additional...

Jul 3, 2026Read Abstract →

Global epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis

CONCLUSION: This systematic review provides updated global ALS burden estimates, showing variations by sex, age, time and geography and underscoring the complex interplay of genetic, environmental and socioeconomic factors, with implications for health planning, resource allocation and etiological research.

Jul 3, 2026Read Abstract →

Development of age-specific and sex-specific blood pressure norms and their associations with lipid profile in children aged 6-16 years from urban Bengaluru: a cross-sectional study

CONCLUSIONS: The study developed updated age-sex and height-specific BP percentiles for Indian children. Findings indicate that elevated BP may coexist with adverse lipid profiles, suggesting early clustering of cardiometabolic risk factors in this population.

Jul 3, 2026Read Abstract →

Navigating the Grey Zone: A Mixed-Methods Study to Evaluate a Decision Support Tool in the SOGC Late Preterm Antenatal Corticosteroids Guideline

CONCLUSIONS: Integrating a DST into the SOGC Technical Update did not increase the frequency or quality of patient-reported counselling, but some obstetricians reported improved knowledge of benefits and harms of late preterm antenatal corticosteroids.

Jul 3, 2026Read Abstract →

The role of micronutrient deficiencies in nutritional anemia beyond iron: An expert perspective on the scope and strength of the current evidence

There is a tacit assumption that the majority of nutritional anemia is caused by iron deficiency. However, several other key micronutrients are involved in iron and/or erythrocyte metabolism and thus play a role in the development of nutritional anemia. This consensus paper provides an updated review that synthesizes current evidence on the role of individual micronutrients, beyond iron, in the development of nutritional anemia and identifies emerging hypotheses and potential mechanistic links...

Jul 3, 2026Read Abstract →

Involvement of cyclins in the pathogenesis of cancer

BACKGROUND: Cyclins are fundamental regulators of the eukaryotic cell cycle, orchestrating cell cycle transitions through their interactions with cyclin-dependent kinases (CDKs). Aberrant expression or activation of cyclins disrupts normal cell cycle control, leading to uncontrolled proliferation, genomic instability, and tumorigenesis. Overexpression of specific cyclins has been documented in multiple malignancies, notably breast cancer, underscoring their oncogenic potential. Despite extensive...

Jul 3, 2026Read Abstract →

Multicentre validation and update of a Legionella prediction score to guide microbiological testing in community-acquired pneumonia

CONCLUSION: The SwissLEGIO score is an easy-to-apply screening tool to rule out LD in hospitalised CAP patients. A scores <2 could reduce Legionella-specific testing by 36-52% (at a disease prevalence of 4%) while maintaining high sensitivity for case detection.

Jul 3, 2026Read Abstract →

Trends in surgical management of hypospadias in Germany: A nationwide analysis on legislative and guideline changes

CONCLUSION: Clinical guideline revisions have a stronger influence on hypospadias surgical practices compared to legislative changes. The temporary decline in procedures during 2019-2021 likely reflects pandemic-related disruptions rather than guideline implementation alone, as surgical volumes have since exceeded pre-pandemic levels. The 2021 legislative change shows no discernible impact on proximal hypospadias correction, even with 43 months of follow-up data suggesting effective preparation...

Jul 3, 2026Read Abstract →