About Us
The Health Thread
Ethical Health Journalism
Live
🌍Ebola Spreads in Eastern DRC and Uganda: UNICEF Warns of Growing Threat to Children🌍Cholera Outbreak Intensifies in Borno, Nigeria: Urgent Health Response Underway🌍Burundi Bolsters Defenses Against Ebola Threat from Neighboring Nations🌍DR Congo Faces Dual Crisis: Food Insecurity Worsens Amidst Spreading Ebola Outbreak🌍Ebola Outbreak in DRC and Uganda: Navigating the Bundibugyo Challenge🌍Ebola Spreads in Eastern DRC and Uganda: UNICEF Warns of Growing Threat to Children🌍Cholera Outbreak Intensifies in Borno, Nigeria: Urgent Health Response Underway🌍Burundi Bolsters Defenses Against Ebola Threat from Neighboring Nations🌍DR Congo Faces Dual Crisis: Food Insecurity Worsens Amidst Spreading Ebola Outbreak🌍Ebola Outbreak in DRC and Uganda: Navigating the Bundibugyo Challenge
Research Watch
•The Heavy Burden of Bullying on Student Wellbeing in Nepal•The Emerging Landscape of Thyroid Health in Central Nepal•How a Recent Western Nepal Study is Redefining Anemia Diagnosis•How H. Pylori is Impacting the Health of Karnali’s High-Altitude Communities•Sweet Poison, Bitter Reality: The Unseen Diabetes Epidemic Among Nepal’s Youth•How Missing Checklists and Protocols are Costing Lives in Nepal’s ERs•Why Your Lungs May Hold the Secret to Your Stress Levels•Walking in Fear: Why Nepal’s Streets Aren't Safe and the Race to Stop a "Hidden Killer"•Why Poor Living and Working Conditions are Shattering the Mental Health of Nepali Workers•Silent Suffering: Why Nepal’s Doctors and Nurses Are Not Reporting Child Abuse•The Heavy Burden of Bullying on Student Wellbeing in Nepal•The Emerging Landscape of Thyroid Health in Central Nepal•How a Recent Western Nepal Study is Redefining Anemia Diagnosis•How H. Pylori is Impacting the Health of Karnali’s High-Altitude Communities•Sweet Poison, Bitter Reality: The Unseen Diabetes Epidemic Among Nepal’s Youth•How Missing Checklists and Protocols are Costing Lives in Nepal’s ERs•Why Your Lungs May Hold the Secret to Your Stress Levels•Walking in Fear: Why Nepal’s Streets Aren't Safe and the Race to Stop a "Hidden Killer"•Why Poor Living and Working Conditions are Shattering the Mental Health of Nepali Workers•Silent Suffering: Why Nepal’s Doctors and Nurses Are Not Reporting Child Abuse

clinical trials

Live updates directly from PubMed Research

Pharmacogenomics of antibacterial and antiviral therapies: Clinical actionability, evidence gaps, and future directions

Anti-infective drugs have profoundly transformed the history of medicine. Yet, with the presence of approximately 4.1-5 million interindividual genomic variants in human genome, patients are expected not to respond equally to the same anti-infective drug. This genetic variability, together with nongenetic factors, influences therapeutic outcomes and contributes to drug-induced adverse events in predisposed individuals. Historically, the identification of HLA-B∗57:01 as a predictor of abacavir...

Jun 15, 2026Read Abstract →

Efficacy of immunotherapy in older adults with triple-negative breast cancer: A systematic review

INTRODUCTION: Immune checkpoint inhibitors (ICI) have transformed the treatment landscape for triple-negative breast cancer (TNBC), but their efficacy in older adults remains unclear. The objective of this systematic review is to evaluate the efficacy of ICI in patients with TNBC aged ≥65 years.

Jun 15, 2026Read Abstract →

A Multilingual Digital Microlearning Intervention for Oral Health in Refugee Shelters: Randomized Controlled Trial

CONCLUSIONS: Brief multilingual digital microlearning improved plaque control and self-reported toothbrushing frequency in refugee shelters. Effects on broader oral health literacy-related outcomes were limited and should be interpreted cautiously. Larger, prospectively powered trials with longer follow-up periods and blinded outcome assessment are warranted.

Jun 15, 2026Read Abstract →

Heterogeneity in Clinical Outcomes Reporting in Minimally-Invasive Facial Rejuvenation: Is It Time for a Core Outcomes Set?

CONCLUSIONS: There is substantial heterogeneity in outcomes reporting among facial rejuvenation studies. Clinicians, researchers, and industry stakeholders should strive to develop a core outcome set to ensure that meaningful and consistent outcomes are reported in all clinical trials.

Jun 15, 2026Read Abstract →

Music Playlist Use in Clinical Trials of Psychedelic Assisted Psychotherapy: A Systematic Review

Recent studies have shown promising results for psychedelics in the treatment of psychiatric disorders. Both in clinical and recreational settings, contextual elements, such as music, can influence the experience of users and may be linked to positive outcomes. This systematic review identifies how music is being selected and used in psychedelisc-assisted psychotherapy (PAP). The search adopted PRISMA criteria and was conducted using PubMed, PsycNet, Web of Science, Scopus and Cochrane as...

Jun 15, 2026Read Abstract →

Defining Cardiovascular Endpoints in Oncology Trials: Challenges and Opportunities: A Scientific Statement From the American Heart Association

The unprecedented expansion of approved oncology therapies has prolonged survival and transformed the prognosis for many patients diagnosed with cancer. However, cancer treatments may be associated with cardiovascular toxicities that manifest through vascular, myocardial, or metabolic pathways, potentially limiting the use of cancer therapeutics and adversely affecting outcomes. Oncology clinical trials provide an important opportunity to evaluate cardiovascular safety signals by generating data...

Jun 15, 2026Read Abstract →

Defining Cardiovascular Endpoints in Oncology Trials: Challenges and Opportunities: A Scientific Statement From the American Heart Association

The unprecedented expansion of approved oncology therapies has prolonged survival and transformed the prognosis for many patients diagnosed with cancer. However, cancer treatments may be associated with cardiovascular toxicities that manifest through vascular, myocardial, or metabolic pathways, potentially limiting the use of cancer therapeutics and adversely affecting outcomes. Oncology clinical trials provide an important opportunity to evaluate cardiovascular safety signals by generating data...

Jun 15, 2026Read Abstract →

Examining the Efficacy of a Telehealth-Based Virtual Reality Clinic in Treating Adults With Specific Phobia: Feasibility Randomized Controlled Trial

CONCLUSIONS: Telehealth-based, multiuser, synchronous VRET is feasible and shows preliminary evidence of efficacy. These findings are promising, and opportunities to improve procedures identified in this feasibility trial will directly inform the protocol for a fully powered RCT evaluating telehealth-based VR and its potential to improve treatment of mental health disorders.

Jun 15, 2026Read Abstract →

A comparative evaluation of on-demand phosphodiesterase-5 inhibitor efficacy in erectile dysfunction treatment: a systematic review and network meta-analysis of double-blind, placebo-controlled, randomized trials

CONCLUSION: PDE5is are highly effective, with sildenafil showing a significantly greater efficacy compared with the other PDE5is.

Jun 15, 2026Read Abstract →

Diode Laser-Assisted Oral Frenectomy as a Modern Alternative: A Systematic Review and Meta-Analysis

CONCLUSIONS: This meta-analysis indicates that diode laser-assisted frenectomy reduces postoperative pain, significantly. In addition, the laser group experienced less intraoperative hemorrhage and better wound healing at 7 day. Future clinical trials should standardize wound-healing indices, define uniform follow-up intervals, and incorporate cost-effectiveness analyses.

Jun 15, 2026Read Abstract →

Effect of Combined Electrowarm Dry Needling on Postpartum Pelvic Girdle Pain: A Randomized Controlled Study

Postpartum pelvic girdle pain (PGP) is a common complication after childbirth, with limited safe and effective treatment options due to the risks of pharmacological interventions in postpartum women. This study aimed to evaluate the efficacy and safety of combined electrowarm dry needling therapy targeting myofascial pain trigger points (MTrPs) for alleviating PGP in postpartum women. A total of 92 postpartum women with PGP were randomly assigned to a treatment group (n = 46) receiving...

Jun 15, 2026Read Abstract →

The effectiveness of a foot-care education program based on multi-theory model in diabetic patients with risk of foot ulceration: A randomized controlled trial protocol

BACKGROUND: Diabetic foot ulcer (DFU) is one of the most common and serious complications of diabetes mellitus (DM). The high disability and fatality rates of DFU raise the importance of early medical treatment. However, delays in seeking medical treatment among DFU patients are common, emphasizing the need for targeted health education. This study aims to evaluate the effectiveness of a Multi-Theory Model (MTM)-based foot care education program on improving healthcare decision-making and foot...

Jun 15, 2026Read Abstract →

Impact of Short and Long Daytime Nap Opportunities on Agility, Aerobic, and Anaerobic Performance in Collegiate Badminton Players

This study investigated the effects of two daytime nap opportunities (40 min and 90 min) on agility, anaerobic performance, and aerobic capacity in collegiate badminton players. Twenty collegiate badminton players participated in a randomized crossover repeated-measures design, including 10 females (age: 20.9 years ± 1.5 years, height: 167.9 cm ± 4.3 cm, weight: 58.3 kg ± 6.1 kg) and 10 males (age: 21.4 years ± 1.4 years, height: 179.7 cm ± 2.8 cm, weight: 73.0 kg ± 3.4 kg). Three experimental...

Jun 15, 2026Read Abstract →

Bayesian re-analysis of ERA223 and PEACE-3 temporal dynamics and bone protection in radium-223-treated metastatic castration-resistant prostate cancer

CONCLUSIONS: Fracture risk was confined to early periods of ERA223 treatment and diminished after the compulsory addition of BPAs in PEACE-3. Due to the limitations of using estimated person-time data and observational comparisons, the findings are best interpreted as descriptive and hypothesis-generating.

Jun 15, 2026Read Abstract →

Quantification of Changes in Bifidobacteria and Lactobacilli Colony-forming Units During Rifaximin Treatment and Synbiotic Gel in Healthy Volunteers

Although the gut microbiota is generally stable, it can be influenced by antibiotic treatment. Rifaximin, which is used to treat gastrointestinal disorders, is frequently administered with probiotics to reduce the risk of dysbiosis. Lactobacillus acidophilus interacts with intestinal cells and uses prebiotic compounds. Bifidobacteria, particularly Bifidobacterium infantis ssp. lactis Bi07, is a probiotic that has been associated with beneficial effects in the gut. In vitro studies have...

Jun 15, 2026Read Abstract →