Bibliometric analysis on the progress of chronic thromboembolic pulmonary hypertension.

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) arises from single or recurrent pulmonary embolism (PE) events, leading to thromboembolic organization, pulmonary vascular obstruction, and subsequent vascular remodeling. Despite extensive research over several decades, a comprehensive bibliometric synthesis of the literature has yet to be performed. Employing CiteSpace and VOSviewer, this study conducted a bibliometric analysis encompassing 2072 journal articles related to CTEPH indexed in the Web of Science (WoS) database, spanning two decades from 2005 to 2025. The analysis encompassed an evaluation of the research landscape, identification of prominent authors, assessment of high-productivity countries and institutions, key journals, and thematic clustering of keywords. The study conducted a bibliometric analysis of over 20 years of CTEPH research, identifying the countries, institutions, authors, journals, and keywords involved in this field. The study analyzed a total of 2072 publications from 67 countries. The top contributors to this field were the United States, Germany, Japan and China. University of California San Diego are the main research institutions. And the journal with the most publications was Pulmonary Circulation. Current research hotspots in this field mainly include the pathophysiological processes, diagnosis and treatment. CTEPH research has expanded over the past two decades, with increasing international contributions and a growing focus on pathophysiology, diagnosis, and multimodal treatment. This bibliometric analysis summarizes the development and current priorities of the field.