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•स्क्रिनमा देखिने चुरोट: सुर्तीजन्य हानि न्यूनीकरण नीतिमा दक्षिण एसियाले अझै के छुटाइरहेको छ•नेपालमा पिसाब नलीको संक्रमण र एन्टिबायोटिक प्रतिरोधको बढ्दो संकट•Frontline Perspectives on Nursing Leadership in Nepal•Protecting the Smallest Lungs from the Hidden Grip of RSV in Kathmandu•The Heavy Burden of Bullying on Student Wellbeing in Nepal•The Emerging Landscape of Thyroid Health in Central Nepal•How a Recent Western Nepal Study is Redefining Anemia Diagnosis•How H. Pylori is Impacting the Health of Karnali’s High-Altitude Communities•Sweet Poison, Bitter Reality: The Unseen Diabetes Epidemic Among Nepal’s Youth•How Missing Checklists and Protocols are Costing Lives in Nepal’s ERs•स्क्रिनमा देखिने चुरोट: सुर्तीजन्य हानि न्यूनीकरण नीतिमा दक्षिण एसियाले अझै के छुटाइरहेको छ•नेपालमा पिसाब नलीको संक्रमण र एन्टिबायोटिक प्रतिरोधको बढ्दो संकट•Frontline Perspectives on Nursing Leadership in Nepal•Protecting the Smallest Lungs from the Hidden Grip of RSV in Kathmandu•The Heavy Burden of Bullying on Student Wellbeing in Nepal•The Emerging Landscape of Thyroid Health in Central Nepal•How a Recent Western Nepal Study is Redefining Anemia Diagnosis•How H. Pylori is Impacting the Health of Karnali’s High-Altitude Communities•Sweet Poison, Bitter Reality: The Unseen Diabetes Epidemic Among Nepal’s Youth•How Missing Checklists and Protocols are Costing Lives in Nepal’s ERs

The UCSC Genome Browser database: 2027 update.

Researchers

Matthew L Speir, Marijke J van Baren, Galt P Barber, Anna Benet-Pages, Johannes Birgmeier, Jonathan Casper, Hiram Clawson, Mark Diekhans, Clay Fischer, Jairo Navarro Gonzalez, Angie S Hinrichs, Christopher M Lee, Luis R Nassar, Gerardo Perez, Brian J Raney, James Robinson, Andrew D Smith, Eliza Alde, Barali Kitiyakara, David Haussler, William James Kent, Maximilian Haeussler

Abstract

Since 2000, the UCSC Genome Browser (https://genome.ucsc.edu) has served as a standard tool for visualizing and comparing annotations across thousands of genome assemblies. Users can browse and visualize a wide range of data types from gene annotations to regulatory regions and comparative genome alignments. Once the data view is configured, the Genome Browser image can be exported for use in publications. Beyond visualization, users can use our tools to compare and export the annotations for further analysis. This year's feature updates include the full release of a tool to copy annotations between related assemblies, QuickLift; feature additions to our data-hosting service HubSpace to enable live editing of configuration files; two new display configurability options: "My Annotations" and custom item coloring; and several improvements to genome assembly discovery and track management. Beyond these new features, 28 new annotation tracks have been added across three broad categories: variant databases and interpretation, gene regulation, and transcriptome and gene expression. These include ENCODE4 cCREs and other ENCODE4 regulatory annotations, variant frequencies and phased variants from national sequencing projects, and two massively parallel reporter assay tracks.
Source: PubMed (PMID: 42984446)View Original on PubMed