Research Watch

New Study Reveals Hidden Environmental Drivers Behind Nepal’s Ongoing Cholera Battle

BySanjogta Thapa MagarMicrobiology Officer & Food Safety Specialist
Published March 4, 2026Updated March 4, 2026

KATHMANDU, Nepal – Despite significant national efforts to eliminate open defecation, a new study suggests that Nepal’s fight against cholera is being undermined by worsening water scarcity and a surprising decline in basic hygiene practices.

The study, titled "Cholera in Nepal: Examining the Role of Environmental Factors in Disease Incidence and Mortality," was recently conducted by researchers Pradip Neupane and Mandawi Subedi. By reviewing ten years of health data from 2013 to 2022, the researchers identified a complex relationship between the environment and the persistence of this deadly, yet preventable, disease.

The 2021 Wake-Up Call For nearly a decade, cholera cases in Nepal remained relatively low and stable. However, the study highlights a dramatic and "noticeable peak" in 2021, when the country saw a massive outbreak of approximately 1,600 cases and 7 recorded deaths. While the numbers dropped significantly in 2022, the sudden spike served as a stark reminder that the bacteria Vibrio cholerae remains a persistent threat in the region.

Success in the Fields, Gaps at the Tap One of the most striking findings of the report is the contrast between different types of sanitation progress. Nepal has seen "substantial progress" in reducing open defecation, with national rates plummeting from 27% in 2013 to below 5% in 2022. Rural areas saw the most dramatic improvement, falling from a 35% practice rate to just 5%.

However, the researchers found that other critical factors are moving in the wrong direction. Access to limited drinking water services—meaning water is either becoming scarcer or harder to access daily—actually increased from 3% to 4.5% during the study period. Even more concerning is the trend in basic hygiene; the percentage of the population lacking handwashing facilities rose from 0.9% to 1.5% by 2022.

"This study shows that water scarcity, open defecation, and handwashing practices are still prevalent in Nepal," the authors noted, explaining that these factors accelerate the transmission of the disease through the "fecal-oral route".

The Climate Change Factor The report also points to rapid climate change as a major driver of shifting disease patterns. Researchers warned that extreme weather events, such as droughts that cause water shortages or floods that contaminate existing supplies, are exposing vulnerable populations to new risks. The World Health Organization has already recognized cholera as one of the primary health threats linked to a changing climate.

A Call for Targeted Action The Government of Nepal has not been idle. The study acknowledges ongoing efforts like the Community Led Water Safe Planning (CLWSP) initiative, a collaboration with UNICEF that certifies "Water Safe Communities" based on strict sanitation and water quality standards. Furthermore, the country has bolstered its surveillance, establishing a call center in 2021 and utilizing media monitoring to catch outbreaks early.

Despite these programs, the researchers conclude that as long as safe drinking water and basic personal hygiene remain out of reach for a portion of the population, cholera will continue to claim lives—particularly among children under five, for whom diarrheal disease is already the second leading cause of death globally.

The findings suggest that for Nepal to truly become cholera-free, the focus must shift from simply building toilets to ensuring every household has a reliable source of clean water and the means to wash their hands.

References (12)
  1. Neupane, P., & Subedi, M. (2026). Cholera in Nepal: Examining the Role of Environmental Factors in Disease Incidence and Mortality. International Journal of Applied and Advanced Multidisciplinary Research (IJAAMR), 4(1), 31-38. DOI: https://doi.org/10.59890/ijaamr.v4i1.161
  2. a. Epidemiological Data and Trends (2013–2022) 2021 peak (~1,600 cases and 7 deaths), the decline in open defecation, and the trends in water scarcity and handwashing were derived from the following institutional reports analyzed in the study's methodology: Epidemiology and Disease Control Division (EDCD): Report 2022 provided by the Department of Health Services (DOHS). Annual reports on disease incidence and mortality. JMP Global Database (WHO/UNICEF): Used for tracking national WASH (Water, Sanitation, and Hygiene) data. https://washdata.org/
  3. b. Climate Change and Disease Patterns
  4. The article's discussion on how rapid climate change affects infectious disease patterns and causes water shortages/excesses is supported by:Lancet. (2019). The 2019 report of the Lancet Countdown on health and climate change. Lancet, 2667(20), 1–82. Dhakal, Y. R., et al. (2016). Research Briefs Building Knowledge for Climate Resilience in Nepal.
  5. Government Initiatives and Surveillance (CLWSP/ECHO)
  6. Information regarding the Community Led Water Safe Planning (CLWSP), Water Safe Certification, and the 2021 call center/surveillance systems is cited from: Paudel, K. P. (n.d.). Nepal Country Update Cholera.
  7. Transmission and Public Health Impact
  8. The description of the "fecal-oral route" and the global impact of diarrheal disease on children under five is supported by: Ali, M., et al. (2015). Updated global burden of cholera in endemic countries. PLoS Neglected Tropical Diseases, 9(6). WHO Fact Sheet. Diarrhoeal disease. (n.d.). https://www.who.int/news-room/fact-sheets/detail/diarrhoeal-disease , Gp, B., et al. (2009). Outbreak Investigation of Diarrheal Diseases in Jajarkot. Journal of Nepal Health Research Council, 7(2), 66–68.
  9. WASH Interventions
  10. The link between poor hygiene/open defecation and the acceleration of fecal-oral diseases is verified by: D’Mello-Guyett, L., et al. (2020). Prevention and control of cholera with household and community water, sanitation and hygiene (WASH) interventions. PLoS ONE, 15(1), 1–26. Chowdhury, F., et al. (2023). The interplay between WASH practices and vaccination with oral cholera vaccines. Vaccine, 41(14), 2368–2375.
  11. Recent Outbreak Documentation
  12. The specific mention of the Kathmandu Valley outbreaks and winter seasonality in Nepal is supported by: Epidemiology and Disease Control Division. Cholera Outbreak in Kathmandu Valley (15th August 2022), Gautam, S., et al. (2012). Cholera: Small outbreak in winter season of Eastern Nepal. North American Journal of Medical Sciences, 4(12), 657–658.

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About the Author
Written By
Sanjogta Thapa Magar
Sanjogta Thapa Magar
Microbiology Officer & Food Safety Specialist

Sanjogta Thapa Magar is a highly skilled Food and Industrial Microbiologist dedicated to enhancing public health through rigorous food safety standards and microbiological research. Currently serving as a Microbiology Officer for the Kathmandu Metropolitan City, she plays

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