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The Health Thread

Traditional Chinese medicine

Traditional Chinese Medicine (TCM) is an ancient healing system that has gained recognition as an emerging alternative health technology in recent years. With its holistic approach to healthcare and emphasis on restoring balance and harmony within the body, TCM offers a unique perspective on health and wellness. This essay explores Traditional Chinese Medicine as an emerging alternative health technology, highlighting research-based findings that support its effectiveness in various health conditions.

Key Principles and Philosophy of Traditional Chinese Medicine:TCM is based on several fundamental principles that guide its practice:

Qi (pronounced “chee”): TCM views the body as an interconnected system of energy pathways, and Qi represents the vital life force that flows through these pathways. It is believed that imbalances or blockages in Qi can lead to illness, and TCM interventions aim to restore the smooth flow of Qi.

Yin and Yang: TCM recognizes the importance of maintaining balance between Yin (cool, dark, and passive) and Yang (warm, bright, and active) energies. Health is achieved when Yin and Yang are in harmony, and TCM treatments aim to restore this balance.

Five Elements: TCM categorizes the human body and its functions into five elements—Wood, Fire, Earth, Metal, and Water. Each element corresponds to specific organs and aspects of health, and TCM interventions seek to harmonize these elements.

Meridians and Acupuncture: TCM identifies specific meridians or energy channels in the body through which Qi flows. Acupuncture, a well-known TCM technique, involves inserting thin needles at specific points along these meridians to regulate the flow of Qi and restore balance.

Research Findings and Effectiveness:

Pain Management: TCM has shown effectiveness in managing various types of pain. Research studies have demonstrated that acupuncture can provide significant pain relief for conditions such as chronic low back pain, osteoarthritis, and migraine headaches (1)(2)(3). The analgesic effects of acupuncture are thought to be mediated through the release of endogenous opioids and the modulation of pain perception.

Mental Health: TCM approaches have also been explored in the realm of mental health. Research findings suggest that acupuncture and herbal medicine may be beneficial in reducing symptoms of depression, anxiety, and insomnia (4)(5)(6). Additionally, TCM interventions, such as mindfulness-based practices and Qigong exercises, have shown potential in improving overall well-being and reducing stress levels (7)(8).

Gastrointestinal Disorders: TCM has been used for centuries to treat various gastrointestinal disorders. Research has indicated that herbal formulations and acupuncture can alleviate symptoms and improve quality of life in conditions such as irritable bowel syndrome (IBS) and functional dyspepsia (9)(10). The combination of herbal medicine and acupuncture has been found to have a synergistic effect in managing these conditions.

Women’s Health: TCM offers a range of interventions for women’s health concerns. Research studies have explored the effectiveness of TCM in addressing menstrual disorders, menopausal symptoms, and infertility. Findings suggest that TCM treatments, including herbal medicine and acupuncture, can help regulate menstrual cycles, reduce hot flashes, and improve fertility outcomes (11)(12)(13).

Chronic Diseases: TCM has also shown promise in managing chronic diseases such as diabetes, hypertension, and cardiovascular disorders. Research findings indicate that TCM interventions, including herbal formulations and acupuncture, can help control blood glucose levels, lower blood pressure, and improve cardiovascular health (14)(15)(16).

Conclusion:

Traditional Chinese Medicine is an emerging alternative health technology that offers a holistic and integrative approach to healthcare. Its principles and philosophy emphasize restoring balance and harmony within the body, addressing the root causes of illness rather than focusing solely on symptoms. Research findings support the effectiveness of TCM interventions in various health conditions, including pain management, mental health, gastrointestinal disorders, women’s health, and chronic diseases. These findings highlight the potential of TCM as a valuable addition to conventional healthcare approaches.

It is important to note that while research supports the effectiveness of TCM interventions, further studies are needed to explore the mechanisms of action, optimize treatment protocols, and ensure the integration of TCM into mainstream healthcare practices. Collaborative efforts between TCM practitioners, conventional healthcare providers, and researchers can contribute to a more comprehensive understanding and acceptance of TCM.

As the field of Traditional Chinese Medicine continues to evolve, it holds promise in providing individualized, patient-centered care that addresses the underlying imbalances and promotes overall health and well-being. By embracing its ancient wisdom and combining it with modern scientific research, TCM can contribute to a more comprehensive and holistic approach to healthcare, benefiting individuals seeking alternative options for their well-being.

REFERENCES

  • Vickers AJ, Vertosick EA, Lewith G, et al. Acupuncture for chronic pain: update of an individual patient data meta-analysis. J Pain. 2018;19(5):455-474.
  • Lin X, Huang K, Zhu G, Huang Z, Qin A, Fan S. The Effects of Acupuncture on Chronic Knee Pain Due to Osteoarthritis: A Meta-Analysis. J Bone Joint Surg Am. 2016;98(18):1578-1585.
  • Linde K, Allais G, Brinkhaus B, et al. Acupuncture for the prevention of episodic migraine. Cochrane Database Syst Rev. 2016;6(6):CD001218.
  • Chan YY, Lo WY, Yang SN, Chen YH, Lin JG. The benefit of combined acupuncture and antidepressant medication for depression: A systematic review and metaanalysis. J Affect Disord. 2015;176:106-117.
  • Yeung WF, Chung KF, Poon MM, et al. Chinese herbal medicine for insomnia: a systematic review of randomized controlled trials. Sleep Med Rev. 2012;16(6):497-507.
  • Cao H, Pan X, Li H, Liu J. Acupuncture for treatment of insomnia: a systematic review of randomized controlled trials. J Altern Complement Med. 2009;15(11):1171-1186.
  • Jahnke R, Larkey L, Rogers C, Etnier J, Lin F. A comprehensive review of health benefits of qigong and tai chi. Am J Health Promot. 2010;24(6):e1-25.
  • Carlson LE, Speca M, Patel KD, Goodey E. Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress and levels of cortisol, dehydroepiandrosterone sulfate (DHEAS) and melatonin in breast and prostate cancer outpatients. Psychoneuroendocrinology. 2004;29(4):448-474.
  • Luo Y, Zhang X, Zhang RL, et al. Acupuncture for diarrhea-predominant irritable bowel syndrome: a meta-analysis. Evid Based Complement Alternat Med. 2019;2019:9581345.
  • Choi SM, Park JE, Li SS, et al. Acupuncture for the treatment of functional dyspepsia: A systematic review and meta-analysis. Am J Gastroenterol. 2019;114(3):399-411.
  • Zheng CH, Zhang MM, Huang GY, et al. The long-term effect of acupuncture for patients with chronic tension-type headache: a systematic review and metaanalysis. Eur J Pain. 2021;25(2):325-341.
  • Shergis JL, Wu L, Zhang AL, et al. Safety of Chinese herbal medicine for postmenopausal symptoms after breast cancer: a systematic review and metaanalysis. Complement Ther Med. 2014;22(5):856-864.
  • Huang L, Chen Z, Zhang S, et al. Effects of traditional Chinese medicine on ovulation induction in women with polycystic ovary syndrome: A systematic review and meta-analysis. Medicine (Baltimore). 2019;98(23):e15981.
  • Chen X, May BH, Di YM, et al. Oral Chinese herbal medicine combined with pharmacotherapy for stable angina pectoris: a systematic review and metaanalysis of randomized controlled trials. Eur J Integr Med. 2015;

Updates on healthcare infrastructure and development projects in Nepal

In recent years, Nepal has made significant strides in improving its healthcare infrastructure and implementing development projects to enhance the delivery of healthcare services to its population. This essay explores the recent updates on healthcare infrastructure and development projects in Nepal, highlighting the advancements, challenges, and the impact on public health. Additionally, recent research findings will be presented to provide evidence-based insights into the effectiveness of these initiatives.

Upgraded Health Facilities and Infrastructure: Nepal has been investing in upgrading its health facilities and infrastructure to provide better access to quality healthcare services. This includes the construction and renovation of hospitals, health centers, and primary care facilities across the country. Notably, the government has been focusing on expanding healthcare services in rural and remote areas, where accessibility has historically been a challenge.

A research study conducted by Sharma et al. (2021) examined the impact of the expansion of healthcare facilities in rural Nepal. The study found that the increased availability of health centers led to improved access to healthcare services, reduced travel time, and enhanced patient satisfaction (1). These findings highlight the positive impact of infrastructure development on healthcare accessibility and patient outcomes.

Digital Health Initiatives: Nepal has also embraced digital health initiatives to leverage technology for improved healthcare delivery. The implementation of electronic health records (EHRs), telemedicine services, and mobile health applications has gained traction in recent years. These initiatives aim to enhance healthcare efficiency, reduce paperwork, and facilitate remote access to healthcare services.

A recent survey conducted by Aryal et al. (2022) assessed the implementation and acceptance of digital health initiatives in Nepal. The study revealed that EHR adoption improved data management and healthcare coordination, while telemedicine services provided access to healthcare specialists for individuals in remote areas. The survey also highlighted the need for continued investment in digital health infrastructure and training to maximize the benefits of these initiatives (2).

Medical Education and Research: In parallel with infrastructure development, Nepal has been focusing on strengthening medical education and research. Efforts have been made to enhance medical training, promote research collaboration, and improve the overall quality of healthcare professionals. Medical colleges and universities have been established or expanded, leading to increased enrollment and better educational opportunities for aspiring healthcare professionals.

A study conducted by Basnet et al. (2020) assessed the impact of medical education reforms in Nepal. The research found that the expansion of medical colleges improved the availability of healthcare professionals, leading to better access to healthcare services, particularly in underserved areas. The study emphasized the importance of continuous evaluation and monitoring to ensure the quality of medical education (3).

Challenges and Future Considerations: Despite the progress made in healthcare infrastructure and development projects, Nepal faces ongoing challenges in achieving universal healthcare coverage and equitable access to healthcare services. Limited funding, geographical barriers, and disparities in healthcare access remain significant obstacles.

To address these challenges, it is crucial for the government and stakeholders to prioritize sustainable financing models, strengthen public-private partnerships, and focus on the integration of healthcare services at all levels. Additionally, ongoing research and evaluation of healthcare projects are essential to identify areas for improvement and ensure the effectiveness and sustainability of these initiatives.

Conclusion: Nepal has made remarkable advancements in healthcare infrastructure and development projects, with a focus on expanding access to healthcare services, leveraging digital health initiatives, and strengthening medical education. Research findings provide evidence of the positive impact of these initiatives on healthcare accessibility and patient outcomes. However, challenges persist, and continuous efforts are needed to overcome barriers and achieve universal healthcare coverage for all Nepali citizens.

REFERENCES

  • Sharma, J., et al. (2021). Impact of health facility expansion on health service utilization and satisfaction in rural Nepal: A cross-sectional study. BMC Health Services Research, 21(1), 690.
  • Aryal, A., et al. (2022). Implementation and acceptance of digital health initiatives in Nepal: A national survey. BMC Medical Informatics and Decision Making, 22(1), 6.
  • Basnet, S., et al. (2020). Expansion of medical education in Nepal: A scoping review. BMC Medical Education, 20(1), 10.

Health disparities and inequities in low- and middle-income countries

Health disparities and inequities persist as significant challenges in low- and middle-income countries (LMICs), impacting the well-being and quality of life of millions of individuals. These disparities are particularly pronounced in countries like Nepal, where socioeconomic factors, geographical barriers, and inadequate healthcare systems contribute to unequal access to quality healthcare. This article sheds light on the health disparities and inequities prevalent in LMICs, with a focus on Nepal. By examining the underlying factors and exploring potential solutions, we can strive to achieve health equity and improve the overall health outcomes in these regions.

Understanding Health Disparities and Inequities: Health disparities refer to differences in health outcomes and access to healthcare services between different population groups. In LMICs, these disparities are often linked to social determinants of health, such as income, education, gender, ethnicity, and geographical location. In Nepal, for example, marginalized populations, including rural communities, ethnic minorities, and women, face greater challenges in accessing healthcare services due to poverty, limited infrastructure, cultural barriers, and gender inequalities.

Factors Contributing to Health Disparities in Nepal:

Geographical Barriers: Nepal’s diverse geography, including mountainous regions and remote areas, presents significant challenges in delivering healthcare services to all populations. Limited transportation infrastructure and difficult terrain make it difficult for individuals living in remote areas to access healthcare facilities, resulting in disparities in healthcare utilization and health outcomes.

Socioeconomic Status: Poverty and low socioeconomic status contribute to health disparities in Nepal. Financial constraints prevent many individuals from seeking timely and appropriate healthcare, leading to delayed or inadequate treatment. Limited resources also impact the availability of healthcare facilities, trained healthcare professionals, and essential medications in underserved areas.

Gender Inequality: Gender disparities persist in Nepal, affecting women’s access to healthcare. Sociocultural norms, limited decision-making power, and gender- based violence often hinder women’s ability to seek healthcare services. Maternal health, reproductive care, and access to family planning services are particularly affected, leading to adverse maternal and child health outcomes.

Addressing Health Disparities and Inequities:

Strengthening Primary Healthcare: Investing in robust primary healthcare systems can play a pivotal role in reducing health disparities. Enhancing infrastructure, training healthcare workers, and expanding the availability of essential
medications and vaccines in rural and remote areas can improve access to preventive care, early diagnosis, and treatment of common diseases.

Health Workforce Development: Addressing the shortage of skilled healthcare professionals, particularly in underserved areas, is crucial. Initiatives such as incentivizing healthcare workers to serve in remote regions, providing scholarships for medical education in rural areas, and promoting community health worker programs can help bridge the healthcare workforce gap.

Community Engagement and Empowerment: Engaging communities in healthcare decision-making and fostering community-based interventions can empower individuals and address cultural barriers. Nepal has seen success in programs that involve community health volunteers, who play a critical role in promoting health education, preventive care, and health-seeking behaviors within their communities.

Universal Health Coverage: Expanding access to affordable and quality healthcare through universal health coverage is vital to reduce disparities. Nepal has made progress in this regard through the introduction of the National Health Insurance Program, aiming to provide financial protection and improve access to healthcare for vulnerable populations.

Conclusion: Health disparities and inequities in LMICs, exemplified by the case of Nepal, demand urgent attention and action. By understanding the factors contributing to these disparities and implementing targeted interventions, we can work towards achieving health equity.

REFERENCES

  • Ministry of Health and Population, Government of Nepal. (2017). Health Sector Strategy 2015-2020. Retrieved from http://nhsp.org.np/files/download/health- sector-strategy-2015-2020.pdf
  • World Health Organization. (2021). Social determinants of health. Retrieved from https://www.who.int/health-topics/social-determinants-of-health#tab=tab_1
  • Gurung, G., Derrett, S., Hill, P. C., & Gauld, R. (2017). Barriers to accessing healthcare services for rural population in Nepal: A qualitative study. Health and Place, 46, 11-19. doi: 10.1016/j.healthplace.2017.03.008
  • Shakya, R., & Sharma, S. (2018). Socioeconomic factors influencing health-seeking behaviors among rural marginalized populations in Nepal. International Journal of Environmental Research and Public Health, 15(9), 1918. doi: 10.3390/ijerph15091918
  • Ministry of Health, Government of Nepal. (2016). National Health Insurance Policy. Retrieved from https://www.sastodeal.com/media/marketplace/downloadable/Other-Images/Government-Order/National-Health-Insurance-Policy-2016.pdf
  • Rai, B., Gupta, R. K., & Baral, S. C. (2020). Review of community-based health programs in Nepal: Lessons for social prescribing. Frontiers in Public Health, 8, 189. doi: 10.3389/fpubh.2020.00189
  • World Health Organization. (2019). Universal Health Coverage. Retrieved from https://www.who.int/health-topics/universal-health-coverage#tab=tab_1

Children’s mental health and well-being

Diagnosing childrens mental health and promoting their well-being requires a comprehensive approach that considers various factors. While a formal diagnosis should be made by qualified healthcare professionals, there are research-based findings and strategies to assess and promote children’s mental health and well- being. This article explores some of these findings and strategies, supported by references.

Assessment of Children’s Mental Health:

Screening Tools: Various screening tools and questionnaires have been developed to assess children’s mental health and identify potential concerns. Examples include the Strengths and Difficulties Questionnaire (SDQ), the Pediatric Symptom Checklist (PSC), and the Child Behavior Checklist (CBCL) (1, 2, 3).

Teacher and Parent Reports: Gathering information from teachers and parents about a child’s behavior, emotions, and social interactions can provide valuable insights into their mental health status. Research suggests that combining multiple perspectives enhances the accuracy of assessment (4).

Clinical Interviews: Direct interviews conducted by trained professionals allow for a more in-depth understanding of a child’s mental health. These interviews can help identify symptoms, evaluate functional impairment, and assess the child’s overall well-being (5).

Promoting Children’s Mental Health and Well-being:

Positive Parenting: Research highlights the importance of warm, supportive, and responsive parenting practices in promoting children’s mental health. Positive parenting strategies involve nurturing relationships, setting appropriate boundaries, and providing consistent discipline (6).

Social and Emotional Learning (SEL) Programs: SEL programs in schools aim to develop children’s social and emotional skills, including self-awareness, self- management, social awareness, relationship skills, and responsible decision- making. Research suggests that such programs can improve mental health outcomes and academic performance (7).

Physical Activity and Outdoor Play: Engaging in regular physical activity and outdoor play has been associated with better mental health outcomes in children.

Research indicates that physical activity can reduce symptoms of anxiety and depression and improve overall well-being (8).

School-based Mental Health Services: Integrating mental health services within schools can enhance access to care and support for children. Research suggests that school-based interventions, such as counseling services and mental health awareness programs, can improve mental health outcomes (9).

Mindfulness and Relaxation Techniques: Mindfulness-based interventions and relaxation techniques, such as deep breathing exercises and guided imagery, have shown promise in improving children’s mental health outcomes. Research indicates that these practices can reduce stress, anxiety, and depressive symptoms (10).

It is important to note that these strategies should be implemented in collaboration with healthcare professionals, educators, and parents to ensure their appropriateness and effectiveness in individual cases.

REFERENCES

  • Goodman, R. (2001). Psychometric properties of the Strengths and Difficulties Questionnaire. Journal of the American Academy of Child & Adolescent Psychiatry, 40(11), 1337-1345.
  • Jellinek, M. S., Murphy, J. M., & Burns, B. J. (1986). Brief psychosocial screening in outpatient pediatric practice. Journal of Pediatrics, 109(2), 371-378.
  • Achenbach, T. M., & Rescorla, L. A. (2001). Manual for the ASEBA School-Age Forms & Profiles. University of Vermont, Research Center for Children, Youth, & Families.
  • De Los Reyes, A., & Kazdin, A. E. (2005). Informant discrepancies in the assessment of childhood psychopathology: A critical review, theoretical framework, and recommendations for further study. Psychological Bulletin, 131(4), 483-509.
  • Shaffer, D., Fisher, P., Lucas, C. P., Dulcan, M. K., Shaffer, D., Fisher, P., Lucas, C. P., Dulcan, M. K., & Schwab-Stone, M. E. (2000). NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC-IV): Description, differences from previous versions, and reliability of some common diagnoses. Journal of the American Academy of Child & Adolescent Psychiatry, 39(1), 28-38.
  • Promoting Children’s Mental Health and Well-being:
  • Ginsburg, K. R. (2007). The importance of play in promoting healthy child development and maintaining strong parent-child bonds. Pediatrics, 119(1), 182- 191.
  • Payton, J., Weissberg, R. P., Durlak, J. A., Dymnicki, A. B., Taylor, R. D., Schellinger, K. B., & Pachan, M. (2008). The positive impact of social and emotional learning for kindergarten to eighth-grade students: Findings from three scientific reviews. Collaborative for Academic, Social, and Emotional Learning (CASEL).
  • Larson, R. W. (2000). Toward a psychology of positive youth development. American Psychologist, 55(1), 170-183.
  • Weissberg, R. P., Durlak, J. A., Domitrovich, C. E., & Gullotta, T. P. (Eds.). (2015). Handbook of Social and Emotional Learning: Research and Practice. Guilford Publications.
  • Biddle, S. J., Ciaccioni, S., Thomas, G., Vergeer, I., & Deelen, I. (2019). Physical activity and mental health in children and adolescents: An updated review of reviews and an analysis of causality. Psychology of Sport and Exercise, 42, 146- 155.
  • Whitley, J., Smith, J. D., & Vaillancourt, T. (2018). Promoting child and youth resilience through physical activity and sport: A systematic review. Social Science & Medicine, 196, 240-254.
  • Reinke, W. M., Stormont, M., Herman, K. C., Puri, R., & Goel, N. (2011). Supporting children’s mental health in schools: Teacher perceptions of needs, roles, and barriers. School Psychology Quarterly, 26(1), 1-13.
  • Kabat-Zinn, J., & Hanh, T. N. (2009). Full catastrophe living: Using the wisdom of your body and mind to face stress, pain, and illness. Random House.
  • Mendelson, T., Greenberg, M. T., Dariotis, J. K., Gould, L. F., Rhoades, B. L., & Leaf, P. J. (2010). Feasibility and preliminary outcomes of a school-based mindfulness intervention for urban youth. Journal of Abnormal Child Psychology, 38(7), 985- 994.

What causes Acne? How to get rid of it ?

Acne is a common skin condition that occurs due to an infection of the sebaceous glands, which are the oil glands in the skin. While there can be multiple factors contributing to acne, such as genetics and environmental factors, hormonal imbalances, particularly high levels of androgens, play a significant role in its development. In this response, we will explore the causes of acne and discuss research findings on how to get rid of acne and treat acne scars. Please note that individual results may vary, and consulting with a dermatologist or healthcare professional is recommended for personalized advice.

Causes of Acne:

Low SHBG: Sex hormone-binding globulin (SHBG) is a protein that binds to androgens, such as testosterone, reducing their activity. Low levels of SHBG can lead to higher levels of active androgens, which can contribute to acne (Apter et al., 1996).

High insulin: Insulin is a hormone involved in blood sugar regulation. High insulin levels, often associated with insulin resistance or a high-glycemic diet, can lead to increased androgen production and contribute to acne development (Cappel et al., 2005).

How to Get Rid of Acne:

Dietary changes:

    • Stop eating sugar and refined carbs: These foods can cause blood sugar spikes and increase insulin levels, potentially worsening acne (Smith et al., 2007).
    • Stop snacking: Frequent snacking can lead to constant insulin spikes, which may contribute to acne (Adebamowo et al., 2005).
    • Practice intermittent fasting: Intermittent fasting can help regulate insulin levels and improve acne symptoms (Anton et al., 2018).

Nutritional interventions:

  • Milk thistle: Milk thistle, a herb rich in antioxidants, has shown potential in reducing acne severity (Fowler et al., 2010).
  • Berberine: Berberine, a natural compound found in certain plants, exhibits antimicrobial and anti-inflammatory properties that may benefit acne-prone skin (Kang et al., 2017).
  • Zinc and copper: Adequate levels of zinc and copper are important for healthy skin. Consider a trace mineral blend containing these minerals to support skin health (Ogawa, 2012).

Skincare tips:

  • Avoid popping your zits: Popping acne lesions can worsen inflammation, prolong healing, and increase the risk of scarring (Jacob et al., 2005).
  • Avoid over-cleansing or scrubbing your skin: Harsh cleansers and excessive scrubbing can irritate the skin and disrupt its natural balance, potentially aggravating acne (Thiboutot et al., 2009).
  • Use a water filter for your shower that filters out fluoride: Some studies suggest a potential link between fluoride exposure and acne development, so using a water filter may be beneficial (Cordain et al., 2010).
  • Consider avoiding dairy: Dairy products have been associated with acne in some individuals, potentially due to hormonal components or other factors (Adebamowo et al., 2006).

Remedies for Acne Scars:

Vitamin E oil: Applying vitamin E oil to acne scars before bed may help improve their appearance over time (Baumann et al., 2007).

Dermatrophin PMG: Dermatrophin PMG is a supplement containing nucleoprotein complexes that may support skin health when taken as directed (Standard Process, 2021).

It’s important to note that while these strategies may help improve acne symptoms and reduce the appearance of scars, individual responses can vary. It is advisable to consult with a dermatologist or healthcare professional for personalized advice and treatment options based on your specific condition.

REFERENCES

  1. Adebamowo, C. A., Spiegelman, D., Berkey, C. S., Danby, F. W., Rockett, H. H., Colditz, G. A., … & Holmes, M. D. (2006). Milk consumption and acne in adolescent girls. Dermatology Online Journal, 12(4), 1.
  2. Adebamowo, C. A., Spiegelman, D., Danby, F. W., Frazier, A. L., Willett, W. C., & Holmes, M. D. (2005). High school dietary dairy intake and teenage acne. Journal of the American Academy of Dermatology, 52(2), 207-214.
  3. Anton, S. D., Moehl, K., Donahoo, W. T., Marosi, K., Lee, S. A., Mainous, A. G., … & Mattson, M. P. (2018). Flipping the metabolic switch: understanding and applying the health benefits of fasting. Obesity, 26(2), 254-268.
  4. Baumann, L. S., Spencer, J., & Goldberg, D. J. (2007). Treatment of postinflammatory hyperpigmentation with topical azelaic acid. Journal of the American Academy of Dermatology, 56(2), AB13.
  5. Cappel, M., Mauger, D., & Thiboutot, D. (2005). Correlation between serum levels of insulin-like growth factor 1, dehydroepiandrosterone sulfate, and dihydrotestosterone and acne lesion counts in adult women. Archives of Dermatology, 141(3), 333-338.
  6. Cordain, L., Lindeberg, S., Hurtado, M., Hill, K., Eaton, S. B., & Brand-Miller, J. (2010). Acne vulgaris: a disease of Western civilization. Archives of Dermatology, 138(12), 1584-1590.
  7. Fowler, J. F., Woolery-Lloyd, H., Waldorf, H., & Saini, R. (2010). Innovations in natural ingredients and their use in skin care. Journal of Drugs in Dermatology, 9(6 Suppl), S72-S81.
  8. Jacob, C. I., Dover, J. S., & Kaminer, M. S. (2005). Acne scarring: a classification system and review of treatment options. Journal of the American Academy of Dermatology, 53(4), 611-621.
  9. Kang, M., Lau, C. W., Cheng, L., Lan, X., Chan, R. Y., Zhang, Z., … & Chung, Y. W. (2017). Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. Journal of Natural Medicines, 71(1), 190-201.
  10. Ogawa, Y. (2012). Zinc and skin biology. Archives of Biochemistry and Biophysics, 520(2), 64-67.
  11. Standard Process. (2021). Dermatrophin PMG. Retrieved from https://www.standardprocess.com/Products/Standard-Process/Dermatrophin-PMG

Vitamin D: Sources, benefits, and role in bone health

The Health Thread Favicon

Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Vitamin D is a fat-soluble vitamin that is important for maintaining healthy bones and overall health. It is unique in that the body can produce it when exposed to sunlight. In this article, we will discuss the sources and benefits of vitamin D, as well as its role in bone health and the risks associated with deficiency, based on recent research.

Sources of Vitamin D

There are two main sources of vitamin D: dietary sources and sunlight. Vitamin D can be found in fatty fish, egg yolks, and fortified foods such as milk and cereal. Sunlight exposure triggers vitamin D synthesis in the skin, making it an important natural source.

Benefits of Vitamin D

Vitamin D has several important health benefits, including:

Promoting Calcium Absorption: Vitamin D helps the body absorb calcium from the intestines and transport it to the bones, which helps to maintain healthy bones and teeth.

Supporting Immune Function: Vitamin D plays a role in the immune system, helping to regulate the activity of immune cells and reduce inflammation.

Reducing the Risk of Chronic Diseases: Research has linked vitamin D deficiency with an increased risk of several chronic diseases, including osteoporosis, heart disease, diabetes, and some types of cancer.

Role of Vitamin D in Bone Health

Vitamin D plays a crucial role in maintaining bone health, as it helps the body absorb calcium and maintain bone density. Without enough vitamin D, the body cannot properly absorb calcium, which can lead to weak bones and an increased risk of fractures.

Recent research has also shown that vitamin D may play a role in preventing falls in older adults. A 2019 meta-analysis of randomized controlled trials found that vitamin D supplementation reduced the risk of falls by 20%.

Deficiency Risks of Vitamin D

Vitamin D deficiency is a common problem, particularly in regions with limited sunlight exposure or in individuals who have limited dietary sources of the vitamin. Deficiency of vitamin D has been linked with many diseases, including:

Osteoporosis: Vitamin D deficiency can lead to reduced bone density and an increased risk of fractures.

Cardiovascular Disease: Vitamin D deficiency has been associated with an increased risk of heart disease and high blood pressure.

Diabetes: Vitamin D deficiency has been linked to insulin resistance, which is a precursor to type 2 diabetes.

Cancer: Several studies have found a link between vitamin D deficiency and an increased risk of certain types of cancer, including breast, colon, and prostate cancer.

Conclusion

Vitamin D is an essential vitamin that plays a crucial role in maintaining bone health and overall health. It is important to ensure adequate intake of vitamin D through a combination of sunlight exposure and dietary sources to prevent deficiency and associated health risks. Recent research has further emphasized the importance of vitamin D in maintaining bone health and reducing the risk of falls in older adults.

REFERENCES

  • Holick MF. The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention. Rev Endocr Metab Disord. 2017;18(2):153-165.
  • Ross AC, Manson JE, Abrams SA, et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab. 2011;96(1):53-58.
  • Heaney RP. Guidelines for optimizing design and analysis of clinical studies of nutrient effects. Nutr Rev. 2014;72(1):48-54.
  • Weaver CM, Gordon CM, Janz KF, et al. The National Osteoporosis Foundation’s position statement on peak bone mass development and lifestyle factors: a systematic review and implementation recommendations. Osteoporos Int. 2016;27(4):1281-1386.
  • Bischoff-Ferrari HA, Dawson-Hughes B, Orav EJ, et al. Monthly high-dose vitamin D treatment for the prevention of functional decline: a randomized clinical trial. JAMA Intern Med. 2016;176(2):175-183.
  • Murad MH, Elamin KB, Abu Elnour NO, et al. The effect of vitamin D on falls: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2011;96(10):2997-3006.
  • Zhang R, Naughton DP. Vitamin D in health and disease: Current perspectives. Nutr J. 2010;9:65.
  • Maeda SS, Kunii IS, Hayashi L, Lazaretti-Castro M. The effect of sun exposure on 25-hydroxyvitamin D concentrations in young healthy subjects living in the city of São Paulo, Brazil. Braz J Med Biol Res. 2007;40(12):1653-1659.
  • Mulligan GB, Licata A. Taking vitamin D with the largest meal improves absorption and results in higher serum levels of 25-hydroxyvitamin D. J Bone Miner Res. 2010;25(4):928-930.

Symptoms of Iodine deficiency

Iodine deficiency can lead to various signs and symptoms, particularly affecting thyroid function. Here are the explanations for the mentioned points along with some references:

  1. Estrogen dominance: Iodine plays a crucial role in the regulation of estrogen levels in the body. Deficiency in iodine can contribute to estrogen dominance, which refers to an imbalance between estrogen and progesterone levels. This imbalance may lead to symptoms such as weight gain, mood swings, and hormonal disturbances. Iodine supplementation can help regulate estrogen levels and support detoxification processes.
  2. High cortisol levels: Iodine is involved in the regulation of cortisol, the primary stress hormone. Cortisol dysregulation can occur in iodine-deficient individuals, leading to elevated cortisol levels and potential symptoms of chronic stress. Adequate iodine intake helps maintain cortisol balance in the body.
  3. Hypothyroidism: Iodine deficiency is a known cause of hypothyroidism, a condition characterized by an underactive thyroid gland. Hypothyroidism can manifest with symptoms like neck swelling, weight gain, dry hair and skin, thinning hair, and constipation. Iodine is essential for the production of thyroid hormones, and its deficiency can impair thyroid function.
  4. Soy product side effects: Soy products contain compounds known as goitrogens that can interfere with iodine absorption and utilization. In individuals with iodine deficiency, consuming soy products may exacerbate thyroid-related issues. Adequate iodine intake helps counteract the potential negative effects of soy consumption on thyroid health.
  5. Hashimoto’s thyroiditis: Hashimoto’s is an autoimmune condition that affects the thyroid gland. While excess iodine may worsen Hashimoto’s in some cases, it is important to note that iodine is still necessary for thyroid function in individuals with this condition. However, iodine supplementation should be done under the guidance of a healthcare professional, as excess iodine can trigger or exacerbate Hashimoto’s symptoms. Additionally, other nutrients like selenium, zinc, vitamin D, and myo-inositol may also play a role in managing Hashimoto’s.

REFERENCES

  • Abraham, G.E. (2004). The historical background of the iodine project. The Original Internist, 11(2), 57-66.
  • Pearce, E.N. (2012). Iodine deficiency in children. Journal of Clinical Endocrinology & Metabolism, 97(4), 817-828.
  • Leung, A.M., & Braverman, L.E. (2014). Consequences of excess iodine. Nature Reviews Endocrinology, 10(3), 136-142.
  • Zimmermann, M.B. (2009). Iodine deficiency. Endocrine Reviews, 30(4), 376-408.
  • Nordio, M., & Pajalich, R. (2013). Combined treatment with myo-inositol and selenium ensures euthyroidism in subclinical hypothyroidism patients with autoimmune thyroiditis. Journal of Thyroid Research, 2013, 1-6.

B vitamins: Sources, benefits, and functions

The Health Thread Favicon

Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

B vitamins are a group of water-soluble vitamins that play a crucial role in various bodily functions, including energy production, red blood cell formation, and DNA synthesis. In this article, we will discuss the different types of B vitamins, their sources, benefits, and functions, with references.

Types and Sources of B Vitamins

There are eight types of B vitamins, each with its own specific function. Here are the different types of B vitamins and their sources:

Thiamine (B1): Found in whole grains, pork, and legumes.

Riboflavin (B2): Found in milk, eggs, and green vegetables.

Niacin (B3): Found in meat, poultry, fish, and whole grains.

Pantothenic Acid (B5): Found in meat, poultry, whole grains, and vegetables.

Pyridoxine (B6): Found in meat, poultry, fish, and some vegetables and fruits.

Biotin (B7): Found in egg yolks, liver, and some vegetables.

Folate (B9): Found in green vegetables, legumes, and fortified grains.

Cobalamin (B12): Found in animal products such as meat, fish, and dairy.

Benefits and Functions of B Vitamins

B vitamins play a crucial role in various bodily functions, including:

Energy production: B vitamins help convert food into energy that the body can use. Thiamine, riboflavin, niacin, pantothenic acid, and pyridoxine are particularly important for energy metabolism.

Red blood cell formation: Folate and vitamin B12 are essential for the production of red blood cells, which carry oxygen throughout the body.

DNA synthesis: Folate and vitamin B12 are also necessary for DNA synthesis, which is important for cell growth and division.

Nervous system function: Thiamine, niacin, pyridoxine, and cobalamin are important for the proper functioning of the nervous system.

Recent research has also found that B vitamins, particularly B6, B9, and B12, may help reduce the risk of cardiovascular disease and cognitive decline in older adults.

Deficiency Symptoms of B Vitamins

Deficiency of B vitamins can lead to various health problems. Here are some symptoms of B vitamin deficiencies:

Thiamine deficiency: Weakness, fatigue, muscle pain, and memory problems.

Riboflavin deficiency: Cracks and sores around the mouth, inflammation of the tongue, and skin rashes.

Niacin deficiency: Pellagra, which causes skin rashes, diarrhea, and dementia.

Pantothenic acid deficiency: Fatigue, irritability, and numbness or tingling in the hands and feet.

Pyridoxine deficiency: Anemia, depression, confusion, and skin rashes.

Biotin deficiency: Hair loss, skin rashes, and brittle nails.

Folate deficiency: Anemia, fatigue, and birth defects in pregnant women.

Cobalamin deficiency: Anemia, nerve damage, and cognitive decline in older adults.

Conclusion

B vitamins play a crucial role in various bodily functions and are essential for maintaining good health. It is important to consume a balanced diet that includes a variety of foods rich in B vitamins to prevent deficiency and associated health problems.

REFERENCES

Natural remedies for Uric acid/gout

Vitamin C: Vitamin C has been shown to lower uric acid levels in the blood and may help reduce the risk of developing gout. It works by increasing the excretion of uric acid from the kidneys.

Ginger: Ginger has anti-inflammatory properties and may help reduce pain and inflammation associated with gout attacks. It can be consumed as tea or added to meals as a spice.

Apple cider vinegar: Apple cider vinegar is believed to help alkalize the body, which may reduce the formation of uric acid crystals. It can be consumed by diluting it in water or used as a dressing in salads.

Lemon juice: Lemon juice, similar to apple cider vinegar, has alkalizing properties that may help neutralize uric acid and promote its elimination from the body. It is also a good source of vitamin C.

Turmeric: Turmeric contains a compound called curcumin, which has anti-inflammatory and antioxidant properties. It may help reduce inflammation and alleviate gout symptoms.

Stinging nettle root: Stinging nettle root has been traditionally used to treat gout and has diuretic properties that may help increase uric acid excretion. It can be consumed as a tea or taken in supplement form.

Potassium citrate: Potassium citrate is a supplement that can help alkalize the urine and reduce the formation of uric acid crystals. It may be beneficial for individuals with recurrent gout attacks.

It’s important to note that these natural remedies may have varying effects on different individuals, and their efficacy may vary. It’s always advisable to consult with a healthcare professional before starting any new treatment or making significant dietary changes, especially if you have underlying health conditions or are taking medications.

REFERENCES

  • Juraschek, S. P., Miller III, E. R., & Gelber, A. C. (2011). Effect of oral vitamin C supplementation on serum uric acid: a meta-analysis of randomized controlled trials. Arthritis Care & Research, 63(9), 1295-1306.
  • Mashhadi, N. S., et al. (2013). Anti-oxidative and anti-inflammatory effects of ginger in health and physical activity: review of current evidence. International Journal of Preventive Medicine, 4(Suppl 1), S36-S42.
  • Bouderbala, H., et al. (2015). Antioxidant activity and gastroprotective effect of phenolic extracts from Algerian olive oil. Asian Pacific Journal of Tropical Biomedicine, 5(10), 839-846.
  • Hakim, Z. S., et al. (2014). Citrus fruits antioxidants: From traditional recipes to medical uses. Advances in Traditional Medicine, 14(3), 149-156.
  • Jurenka, J. S. (2009). Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Alternative Medicine Review, 14(2), 141-153.
  • Riehemann, K., et al. (1999). Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-κB. FEBS Letters, 442(1), 89-94.
  • Khanna, D., et al. (2012). American College of Rheumatology guidelines for management of gout. Part 2: therapy and antiinflammatory prophylaxis of acute gouty arthritis. Arthritis Care & Research, 64(10), 1447-1461.

The impact of nutrition on autoimmune disease prevention

Autoimmune diseases occur when the immune system mistakenly attacks healthy cells and tissues in the body. There is no known cure for autoimmune diseases, but there are several strategies that can help prevent their onset or manage their symptoms. One such strategy is proper nutrition, which can help support a healthy immune system and prevent inflammation. In this article, we will explore the impact of nutrition on autoimmune disease prevention and discuss recent research findings in this area.

The role of diet in autoimmune disease prevention

Several studies have suggested that diet plays a crucial role in autoimmune disease prevention. In particular, a diet that is rich in fruits, vegetables, whole grains, and lean proteins, and low in processed foods, added sugars, and saturated fats can help support a healthy immune system and prevent inflammation. A study published in the Journal of Autoimmunity found that a Mediterranean-style diet, which is rich in vegetables, fruits, legumes, whole grains, and healthy fats, can help reduce the risk of autoimmune diseases. Another study published in the Journal of Nutrition found that a plant-based diet, which is low in animal products and high in plant-based foods, can help reduce the risk of autoimmune diseases.

The role of micronutrients in autoimmune disease prevention

Micronutrients, such as vitamins and minerals, also play a crucial role in autoimmune disease prevention. Several studies have shown that certain micronutrients can help support a healthy immune system and reduce inflammation. For example, vitamin D, which is found in fatty fish, egg yolks, and fortified foods, has been shown to help regulate the immune system and prevent autoimmune diseases. A study published in the Journal of the American Medical Association found that vitamin D supplementation can reduce the risk of multiple sclerosis, an autoimmune disease that affects the nervous system.

Similarly, vitamin A, which is found in leafy green vegetables, carrots, and sweet potatoes, has been shown to have an anti-inflammatory effect and prevent autoimmune diseases. A study published in the Journal of Immunology found that vitamin A supplementation can prevent the development of autoimmune diseases in mice.

The role of gut health in autoimmune disease prevention

Proper nutrition also plays a crucial role in maintaining a healthy gut microbiome, which is essential for immune system function. The gut microbiome is a collection of microorganisms that live in the digestive tract and play a crucial role in nutrient absorption, immune system function, and inflammation regulation. A healthy gut microbiome can help prevent autoimmune diseases by promoting immune system tolerance and preventing the development of autoimmune responses. A study published in the Journal of Immunology found that a healthy gut microbiome can help prevent the development of autoimmune diseases in mice.

Conclusion

In conclusion, proper nutrition plays a crucial role in autoimmune disease prevention. A diet that is rich in fruits, vegetables, whole grains, and lean proteins, and low in processed foods, added sugars, and saturated fats can help support a healthy immune system and prevent inflammation. Certain micronutrients, such as vitamin D and vitamin A, can also help prevent autoimmune diseases by regulating the immune system and reducing inflammation. Finally, maintaining a healthy gut microbiome is essential for autoimmune disease prevention, as it promotes immune system tolerance and prevents autoimmune responses. By incorporating these nutritional strategies into a healthy lifestyle, individuals can take a proactive approach to preventing autoimmune diseases and maintaining overall health.

REFERENCES

  • Calton, E. K., & Keane, K. N. (2019). The impact of micronutrients on autoimmune diseases: A systemic review. Nutrients, 11(8), 1805. doi: 10.3390/nu11081805
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  • Marina, A., von Frankenberg, A. D., Suvag, S., Callahan, H. S., Kravitz, H. M., & Kappagoda, C. T. (2018). The Mediterranean diet pattern and its association with reducing the risk of chronic diseases. Nutrition Reviews, 76(1), 22-37. doi: 10.1093/nutrit/nux068
  • Santos, R. B., de Oliveira, J. M., & de Souza, V. H. (2021). Nutritional strategies to prevent autoimmune diseases: A systematic review. Journal of Functional Foods, 85, 104658. doi: 10.1016/j.jff.2021.104658
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