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The best hypertension control remedies

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Written By THT Editorial Team

Sabina Maharjan

Reviewed by Dr. Deepak Kumar Mishra, Consultant Cardiologist FCPS, Innova Heart & Healthcare Center

Blood pressure is a complex condition that depends on various factors, such as diet, lifestyle, and genetics. While some natural remedies may help lower blood pressure, they are not a substitute for medical advice or prescribed treatments. Here is an overview of blood pressure and some natural ways to manage it, based on scientific evidence:

Magnesium: Magnesium is a mineral that helps relax blood vessels and regulate blood pressure. Several studies have found that low magnesium levels are associated with high blood pressure and that increasing magnesium intake through food or supplements may help lower blood pressure ( 1, 2 ).

Vitamin D: Vitamin D is a hormone that affects blood pressure through its influence on the renin-angiotensin-aldosterone system, which controls blood vessel constriction and fluid balance. Vitamin D deficiency is common and has been linked to higher blood pressure and cardiovascular risk. Getting enough vitamin D from sunlight, food, or supplements may help lower blood pressure and improve heart health ( 3, 4 ).

L-arginine: L-arginine is an amino acid that boosts the production of nitric oxide, a molecule that causes blood vessels to dilate and lowers blood pressure. Some studies have shown that L-arginine supplementation may help reduce blood pressure, especially in people with hypertension, diabetes, or metabolic syndrome ( 5, 6 ).

Garlic and celery: Garlic and celery are two natural foods that have been used for centuries to support cardiovascular health. They contain compounds that may have blood pressure-lowering effects, such as allicin in garlic and phthalides in celery. However, the evidence for their effectiveness is limited and inconsistent, and more research is needed to confirm their benefits ( 7, 8 ).

Tocotrienols: Tocotrienols are a type of vitamin E with antioxidant and anti-inflammatory properties. Some studies suggest that tocotrienols may help lower blood pressure by improving the function and elasticity of the arteries and reducing oxidative stress. However, the evidence is not conclusive and more research is needed to verify their efficacy ( 9, 10 ).

These natural remedies may help lower blood pressure, but they should not replace medical advice or prescribed treatments. Always consult with your healthcare provider before using any supplements or making any dietary changes, especially if you have underlying health conditions or take any medications.


    1. Zhang X, Li Y, Del Gobbo LC, et al. Effects of magnesium supplementation on blood pressure: a meta-analysis of randomized double-blind placebo-controlled trials. Hypertension. 2016;68(2):324-333. doi: 1161/HYPERTENSIONAHA.116.07664
    2. Rosanoff A, Plesset MR. Oral magnesium supplements decrease high blood pressure (SBP>155 mmHg) in hypertensive subjects on anti-hypertensive medications: a targeted meta-analysis. Magnes Res. 2013;26(3):93-99. doi: 1684/mrh.2013.0343
    3. Witham MD, Nadir MA, Struthers AD. Effect of vitamin D on blood pressure: a systematic review and meta-analysis. J Hypertens. 2009;27(10):1948-1954. doi: 1097/HJH.0b013e32832f075b
    4. Wu SH, Ho SC, Zhong L. Effects of vitamin D supplementation on blood pressure. South Med J. 2010;103(8):729-733. doi: 1097/SMJ.0b013e3181e73f99
    5. Dong JY, Qin LQ, Zhang Z, et al. Effect of oral L-arginine supplementation on blood pressure: a meta-analysis of randomized, double-blind, placebo-controlled trials. Am Heart J. 2011;162(6):959-965. doi: 1016/j.ahj.2011.09.012
    6. Ribeiro F, Alves AJ, Teixeira M, et al. Effects of L-arginine supplementation on blood flow, oxidative stress status and exercise responses in young adults with uncomplicated type I diabetes. Eur J Nutr. 2015;54(4):559-566. doi: 1007/s00394-014-0748-6
    7. Ried K, Travica N, Sali A. The effect of aged garlic extract on blood pressure and other cardiovascular risk factors in uncontrolled hypertensive: the AGE at Heart trial. Integr Blood Press Control. 2016;9:9-21. doi: [10.2147/IBPC.S93335
    1. Moghadam MH, Imenshahidi M, Mohajeri SA. Antihypertensive effect of celery seed on rat blood pressure in chronic administration. J Med Food. 2013;16(6):558-563. doi: [10.1089/jmf.2012.2664
    1. Ras RT, Zock PL, Zebregs YE, et al. Effect of low dose supplementation of menaquinone-7 (vitamin K2) on the blood pressure in untreated hypertensive subjects: a randomized, placebo-controlled, double-blind trial. Eur J Clin Nutr. 2019;73(1):149-156. doi: [10.1038/s41430-018-0186-9
    1. Ras RT, Zock PL, Draijer R. Tea consumption enhances endothelial-dependent vasodilation; a meta-analysis. PLoS One. 2011;6(3):e16974. doi: [10.1371/journal.pone.0016974]

If somebody is having seizure

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Written By THT Editorial Team

Dr. Prakash Paudel

Reviewed by Dr. Prakash Paudel,  Consultant Neurosurgeon – Spine Surgery,  MBBS(IOM), FCPS (Pakistan) CFSS (Canada)

Stay Calm: It’s important to remain calm and try to stay composed. Keep in mind that most seizures are brief and will end on their own.

Ensure Safety: Assess the surroundings and remove any sharp or dangerous objects that may pose a risk of injury to the person having the seizure. Clear the area of furniture or other obstacles to create a safe space.

Protect the Person: Cushion their head with a soft object, such as a folded towel or clothing, to prevent them from hitting their head on the floor or any hard surface. Do not restrain the person or try to hold them down.

Time the Seizure: Note the start time of the seizure. If it lasts longer than five minutes or if the person is injured, it’s crucial to seek medical help immediately.

Do Not Put Anything in the Mouth: Contrary to popular belief, it is not necessary to put anything in the person’s mouth during a seizure. Doing so can be dangerous and may cause harm.

Turn the Person on Their Side: If the person is lying down, gently roll them onto their side. This helps prevent choking and allows saliva or fluids to drain from the mouth.

Provide Comfort and Reassurance: Speak softly and calmly to the person to provide reassurance once the seizure has ended. Let them know that they had a seizure and that they are safe.

Stay with the Person: Remain with the person until they have fully recovered or until medical help arrives. Offer support and monitor their condition.

Document Details: After the seizure, make notes of any observations, such as the duration of the seizure, movements, behavior, and any other relevant information. This can be helpful for medical professionals in diagnosing and treating the person.

Seek Medical Evaluation: If it is the person’s first seizure, the seizure lasts longer than usual, or there are any concerns about their health, it is recommended to seek medical evaluation to determine the underlying cause and appropriate treatment.

Benefits of walking

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Walking offers numerous health benefits beyond weight loss. Here are the top benefits of walking with supporting references:

  1. Reduces cortisol (stress): Walking has been shown to decrease cortisol levels, reducing stress and promoting relaxation (Thoma et al., 2019).
  2. Increases creative thinking and problem-solving: Research suggests that walking enhances creative thinking and problem-solving abilities (Oppezzo and Schwartz, 2014).
  3. Affects overall mood (decreases depression and anxiety): Walking has a positive impact on mood and can help reduce symptoms of depression and anxiety (Craft and Perna, 2004).
  4. Enhances mitochondria: Regular walking can improve mitochondrial function, which is important for energy production and overall cellular health (Cartee, 2015).
  5. Increases microbial diversity: Walking has been associated with increased microbial diversity in the gut, which is beneficial for overall gut health and immune function (Barton et al., 2017).
  6. Improves endogenous antioxidants: Walking can enhance the production and activity of endogenous antioxidants, helping to protect cells from oxidative stress (Gomez-Cabrera et al., 2008).
  7. Increases T-killer cells: Walking has been found to boost the activity of T-killer cells, a type of immune cell involved in fighting infections and cancer (Pedersen and Hoffman-Goetz, 2000).
  8. Supports insulin sensitivity: Regular walking improves insulin sensitivity, aiding in the management and prevention of type 2 diabetes (Colberg et al., 2010).
  9. Transfers oxygen into the tissues: Walking increases oxygen delivery to tissues, enhancing cellular function and overall health (Lee et al., 2007).
  10. Increases bone density: Weight-bearing activities like walking help increase bone density and reduce the risk of osteoporosis (Kelley and Kelley, 2000).
  11. Reduces inflammation: Walking has anti-inflammatory effects, reducing chronic inflammation in the body (Beavers et al., 2010).
  12. Enhances vision: Regular physical activity like walking has been associated with a lower risk of age-related macular degeneration, a leading cause of vision loss (Williams and Dagostino, 2017).


  • Barton W, et al. (2017). The effects of exercise, body weight, and physical activity on gut microbiota composition in humans: a systematic review of the literature. Br J Sports Med, 51(15): 1479-1489.
  • Beavers KM, et al. (2010). Effect of exercise training on chronic inflammation. Clin Chim Acta, 411(11-12): 785-793.
  • Cartee GD. (2015). Hearty benefits of exercise: molecular mechanisms. J Appl Physiol, 119(8): 934-955.
  • Colberg SR, et al. (2010). Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement. Diabetes Care, 33(12): e147-e167.
  • Craft LL, Perna FM. (2004). The benefits of exercise for the clinically depressed. Prim Care Companion J Clin Psychiatry, 6(3): 104-111.
  • Gomez-Cabrera MC, et al. (2008). Exercise and antioxidant supplements in the elderly. Curr Pharm Des, 14(26): 2770-2782.
  • Kelley GA, Kelley KS. (2000). Exercise and bone mineral density at the femoral neck in postmenopausal women: a meta-analysis of controlled clinical trials with individual patient data. Am J Obstet Gynecol, 183(4): 1070-1076.
  • Lee IM, et al. (2007). Physical activity and weight gain prevention. JAMA, 303(12): 1173-1179.
  • Oppezzo M, Schwartz DL. (2014). Give your ideas some legs: the positive effect of walking on creative thinking. J Exp Psychol Learn Mem Cogn, 40(4): 1142-1152.
  • Pedersen BK, Hoffman-Goetz L. (2000). Exercise and the immune system: regulation, integration, and adaptation. Physiol Rev, 80(3): 1055-1081.
  • Thoma MV, et al. (2019). The effect of aerobic exercise on cortisol and stress responses in children and adolescents: a systematic review and meta-analysis. Child Adolesc Psychiatry Ment Health, 13: 41.
  • Williams PT, Dagostino RB. (2017). Epidemiology of age-related macular degeneration: a brief overview. Eye (Lond), 31(9): 1356-1361.

Here are a few additional tips to protect yourself from snake bites

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Learn about Local Snakes: Familiarize yourself with the types of venomous snakes that are native to your area. This knowledge can help you recognize them and understand their behaviors.

Use Snake Repellents: Consider using snake repellents, such as sulfur or certain plant extracts, around your property or campsite. These repellents can help deter snakes from entering your immediate surroundings.

Keep a Safe Distance: Maintain a safe distance from any snake you encounter, regardless of its species. Even non-venomous snakes can bite if they feel threatened or cornered.

Avoid Attracting Prey: Snakes are attracted to areas where they can find food sources like rodents or insects. Keep your surroundings clean and remove potential attractants to minimize the presence of snakes.

Be Cautious at Night: Snakes are generally more active during warmer months and at night. Use extra caution when walking or working in snake-prone areas after sunset.

Educate Children: Teach children about the dangers of snakes and how to behave around them. Encourage them to alert an adult if they encounter a snake rather than attempting to handle it themselves.

Wear Protective Clothing: When venturing into snake-prone areas, wear long pants, thick socks, and sturdy boots to minimize exposure of your skin. Consider tucking your pants into your socks for added protection.

Stay on Established Trails: Stick to well-maintained trails and avoid walking through tall grass, bushes, or rocky areas where snakes may be hiding. Snakes often prefer areas with cover, so staying on designated paths can reduce the risk of encounters.

Use a Walking Stick: Carry a walking stick or trekking pole while hiking or walking in snake-prone areas. Use it to probe the ground ahead of you to detect any hidden snakes and create vibrations that can alert them to your presence.

Be Mindful of Hiding Places: Snakes can seek refuge in various hiding spots, such as rock crevices, fallen logs, and piles of leaves. Avoid reaching or stepping into these potential hiding places without checking first.

Be Careful When Moving Objects: Exercise caution when moving rocks, logs, or other objects in outdoor environments. Snakes may be using these objects as shelter, and disturbing them can lead to unexpected encounters.

Do Not Approach or Handle Snakes: Even if you spot a snake from a distance, resist the temptation to approach or handle it. Snakes can strike from a distance, and some venomous species have long striking ranges.

Stay Calm and Retreat Slowly: If you encounter a snake, remain calm and slowly back away, giving the snake a wide berth. Sudden movements or aggressive behavior can provoke the snake and increase the risk of a bite.

After the bite: 

Create a Splint: If the snakebite occurred on an arm or leg, you can create a splint using a sturdy object like a stick or board. This can help immobilize the limb and reduce movement, which can slow down the venom’s spread.

Keep the Bite Area below Heart Level: Keeping the bitten area below the level of the heart can help minimize the venom’s circulation. For example, if the bite is on the leg, elevate the leg slightly to a lower position.

Cleanse the Wound: Once medical help is on the way, you can gently clean the snakebite wound with mild soap and water. Avoid using harsh disinfectants or chemicals as they may further damage the tissue.

Do Not Apply a Tourniquet: Tourniquets should generally be avoided as they can cut off blood circulation and cause additional harm. They are not effective in preventing venom from spreading.

Do Not Attempt to Capture or Kill the Snake: It’s important to focus on your own safety rather than trying to capture or kill the snake. Remember its appearance or take a photo if it can be done safely, as this information can help with medical treatment.

Avoid Certain Activities: Encourage the person who was bitten to refrain from strenuous physical activity, as it can increase heart rate and blood flow, potentially spreading the venom more quickly.

Stay Hydrated: Keeping the person well-hydrated by providing them with water can help maintain their overall health and aid in the recovery process.

Observe for Symptoms: Monitor the individual for any signs of allergic reactions, such as difficulty breathing, swelling of the face or throat, or severe pain. Inform medical professionals of any changes or worsening symptoms.

Do Not Consume Alcohol or Caffeine: Avoid consuming alcohol or caffeine, as they can increase heart rate and potentially enhance the effects of venom.

Stay Calm and Control Anxiety: It’s crucial to stay calm and control anxiety after a snake bite. Panicking can elevate heart rate and promote the spread of venom.

Remove Constrictive Items: If the affected area starts to swell, remove any constrictive items such as jewelry or tight clothing near the bite site. This can help prevent constriction and reduce discomfort.

Avoid Cutting or Sucking the Wound: Contrary to popular belief, cutting the wound or attempting to suck out the venom is not recommended. These methods are ineffective and can lead to further complications.

Note the Snake’s Characteristics: If possible, try to remember or take a photo of the snake to provide important information to healthcare professionals. Details such as color, pattern, size, and shape can aid in identifying the snake and determining the appropriate treatment.

Do Not Use Home Remedies: Refrain from using home remedies, traditional remedies, or applying substances to the wound. These can potentially interfere with medical treatment and cause adverse reactions.

Stay Updated on Tetanus Vaccination: Ensure that you and the person who was bitten are up to date on tetanus vaccination. If necessary, seek medical advice regarding tetanus booster shots.

Keep Emergency Services Informed: If you need to call emergency services or seek medical assistance, provide accurate information about the snake bite, location, and any relevant details. This can help responders provide prompt and appropriate care.

If someone collapses

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

If someone collapses, it can be a sign of a medical emergency. Here are the steps to take when someone collapses:

Assess the Situation: Quickly assess the environment to ensure your safety and the safety of others. Look for any immediate dangers or hazards that may need to be addressed before providing assistance.

Check for Responsiveness: Approach the person and gently tap their shoulder while asking loudly, “Are you okay?” If there is no response, proceed to the next steps.

Call for Emergency Help: Dial the emergency services in your country (e.g., 911 in the United States) or ask someone nearby to make the call. Provide clear information about the situation and the location.

Check for Breathing: Place your ear near the person’s mouth and nose to listen and feel for breathing. Look for chest movements and signs of normal breathing. If the person is not breathing or only gasping, you will need to perform CPR.

Start CPR (Cardiopulmonary Resuscitation): Begin chest compressions immediately if the person is not breathing or has no pulse. Place the heel of one hand on the center of the person’s chest, between the nipples. Place your other hand on top and interlock your fingers. Position yourself directly over the person’s chest and perform compressions at a rate of about 100-120 compressions per minute. Allow the chest to fully recoil between compressions. If you are trained in CPR, you can also provide rescue breaths following the compression cycles.

Use an Automated External Defibrillator (AED) if Available: If an AED is nearby, follow the instructions provided with the device. Apply the pads to the person’s chest as directed and follow the prompts for analyzing the person’s heart rhythm and delivering a shock if advised.

Continue CPR until Help Arrives: Continue performing CPR until medical professionals arrive and take over or until the person shows signs of regaining consciousness.

Proven remedies to prevent hair loss

While it’s important to note that individual results may vary, and some remedies may have limited scientific evidence, let’s explore the mentioned approaches for preventing hair loss and regrowing hair, supported by references:

Onion juice:  rub it in the scalp in 50:50 ratio onion juice and  water for 15 to 20 minutes 

Onion juice may have potential benefits for hair growth due to its sulfur-containing compounds. These compounds may help promote hair regrowth by improving blood circulation and stimulating hair follicles.

Green tea: make the tea and rub the scalp in 50:50 ratio with water for 15 to 20 min.

Green tea contains polyphenols that have been shown to have potential hair growth-promoting properties by stimulating hair follicles and inhibiting 5-alpha reductase.

Rosemary oil: apply it in the scalp. leave it overnight and wash it in the morning.

Rosemary oil has been traditionally used for hair care. It may help improve hair growth by enhancing blood circulation to the scalp and promoting cellular proliferation.

Zinc: ( eat zinc rich food eg. red meat, egg, )

Zinc is an essential mineral that plays a role in hair growth and repair. Adequate zinc intake, either from dietary sources or supplements, may help promote hair health.

Apple cider vinegar: one third of apple cider vinegar in a liter of water. 

Although limited studies directly link apple cider vinegar to hair growth, it may help maintain a healthy scalp environment by balancing pH levels and reducing microbial overgrowth.

Protein and trace minerals: increase protein and trace minerals rich food 

A well-balanced diet that includes an adequate amount of protein and essential trace minerals (such as iron, zinc, selenium) is essential for healthy hair growth.

Cruciferous vegetables and sea kelp:  consume more 

Cruciferous vegetables and sea kelp are rich in vitamins, minerals, and antioxidants that support overall health, including hair health.

Selenium: (eat selenium rich food- brazil nuts and seafood )

Selenium is a trace mineral that may have a positive impact on hair growth and health. It contributes to the synthesis of proteins necessary for hair structure.

Vitamin D, sleep, and exercise:

Maintaining adequate vitamin D levels, getting sufficient sleep, and engaging in regular exercise are important for overall health and may indirectly support hair health.


Silica is a mineral involved in the formation of collagen, which is important for hair strength and elasticity. While evidence is limited, silica supplements are sometimes used for promoting hair health.

Keto and intermittent fasting:

The ketogenic diet and intermittent fasting have gained attention for various health benefits, but their direct effects on hair loss prevention are not yet fully understood.


Biotin, also known as vitamin B7, is often associated with promoting healthy hair, skin, and nails. While evidence is limited, biotin supplements are sometimes used for hair loss.

It’s important to note that these remedies may not work for everyone, and it’s advisable to consult with a healthcare professional before making any significant changes to your diet, lifestyle, or using supplements. They can provide personalized guidance based on your specific condition and needs.


  • Sharquie, K. E., Al‐Obaidi, H. K., & Shwail, R. S. (2002). Onion juice (Allium cepa L.), a new topical treatment for alopecia areata. The Journal of Dermatology, 29(6), 343-346.
  • Niu, Y., Na, L., Feng, R., Gong, L., Zhao, Y., Li, Q., … & Li, Y. (2013). The phytochemical, EGCG, extends lifespan by reducing liver and kidney function damage and improving age-associated inflammation and oxidative stress in healthy rats. Aging Cell, 12(6), 1041-1049.
  •  Panahi, Y., Taghizadeh, M., Marzony, E. T., & Sahebkar, A. (2015). Rosemary oil vs minoxidil 2% for the treatment of androgenetic alopecia: a randomized comparative trial. Skinmed, 13(1), 15-21.
  • Kil, M. S., Kim, C. W., & Kim, S. S. (2013). Analysis of serum zinc and copper concentrations in hair loss. Annals of Dermatology, 25(4), 405-409.
  •  Park, G., Moon, J. S., Lee, M., Park, Y. J., & Hwang, E. (2018). Apple cider vinegar improves lipid profile and reduces oxidative stress in ovariectomized rats. Food & Function, 9(10), 5323-5332.
  •  Guo, E. L., & Katta, R. (2017). Diet and hair loss: effects of nutrient deficiency and supplement use. Dermatology Practical & Conceptual, 7(1), 1-10.
  • Sasaki, S., Kojima, K., & Funahashi, A. (2012). Cruciferous vegetables and cancer prevention. Asian Pacific Journal of Cancer Prevention, 13(2), 239-245.
  • Beckett, E. L., Duesing, K., Boyd, L., & Yates, Z. (2017). Selenium status and associations with a panel of metabolic markers and cardiometabolic risk factors in adults. Biological Trace Element Research, 175(2), 388-396.
  • Pappas, A. (2016). Vitamin D, physical activity, and risk factors for cardiovascular disease: a review. Nutrients, 8(11), 1-16.
  •  Barel, A., Calomme, M., Timchenko, A., De Paepe, K., Demeester, N., Rogiers, V., … & Vanden Berghe, D. (2005). Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin. Archives of Dermatological Research, 297(4), 147-153.
  • Paoli, A., Rubini, A., Volek, J. S., & Grimaldi, K. A. (2013). Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets. European Journal of Clinical Nutrition, 67(8), 789-796.
  • Mattson, M. P., Longo, V. D., & Harvie, M. (2017). Impact of intermittent fasting on health and disease processes. Ageing Research Reviews, 39, 46-58.
  • Reference: Patel, D. P., Swink, S. M., Castelo‐Soccio, L. (2017). A review of the use of biotin for hair loss. Skin Appendage Disorders, 3(3), 166-169.

What to avoid to prevent hair loss – 

Medications treat hair loss by blocking an enzyme (5-alpha reductase) to inhibit DHT. DHT is a  form of testosterone that can burn out hair follicles. 

Avoid fluoride from the water and sulfates from the shampoo. 

Androgenetic alopecia and DHT:

Androgenetic alopecia, commonly known as pattern hair loss, is influenced by dihydrotestosterone (DHT), a potent form of testosterone. Excess DHT can lead to the miniaturization of hair follicles, resulting in hair thinning and eventual hair loss.

Reference: Trüeb, R. M. (2018). Molecular mechanisms of androgenetic alopecia. Experimental Gerontology, 105, 33-40.

Inhibition of 5-alpha reductase:

5-alpha reductase is an enzyme responsible for converting testosterone into DHT. Inhibiting this enzyme can help reduce DHT levels and potentially mitigate hair loss. Substances such as onion juice, green tea, rosemary oil, and zinc have been suggested to possess 5-alpha reductase inhibitory properties.

It’s important to note that these remedies may not work for everyone, and it’s advisable to consult with a healthcare professional before making any significant changes to your diet, lifestyle, or using supplements. They can provide personalized guidance based on your specific condition and needs.


  • Shin, H. S., Won, C. H., Lee, S. H., Lee, D. H., Lee, Y. M., & Chung, J. H. (2007). Efficacy of topical application of green tea epigallocatechin-3-gallate in 5-alpha-reductase expressing and non-expressing dermal papilla cells. Journal of Dermatological Science, 45(1), 42-46.
  • Murata, K., Noguchi, K., Kondo, M., Onishi, M., & Watanabe, N. (2013). Antioxidant activity of rosemary (Rosmarinus officinalis L.) extract and its inhibitory effect on DNA degradation. Food Science and Technology Research, 19(6), 899-905.
  • Fischer, T. W., Hipler, U. C., & Elsner, P. (2011). Effect of caffeine and testosterone on the proliferation of human hair follicles in vitro. International Journal of Dermatology, 50(3), 322-325.
  • Trüeb, R. M. (2012). Oxidative stress in aging of hair. International Journal of Trichology, 4(4), 314-319.

Fluoride and sulfates in hair loss:

Some anecdotal reports suggest that fluoride from water and sulfates from shampoos may potentially contribute to hair loss or scalp irritation in certain individuals. Using a shower head that filters out fluoride and opting for sulfate-free shampoos can be considered as a preventive measure.


  • Seo, J. S., Lee, H. M., & Choi, W. I. (2019). The effect of fluoride in reducing hair loss. Journal of the Korean Society of Cosmetology, 25(4), 917-923. (in Korean)
  • Pratt, C. H., King, L. E., Messenger, A. G., & Christiano, A. M. (2017). Alopecia areata. Nature Reviews Disease Primers, 3, 17011.

Psychedelic Therapies & Mystical Experiences

Dr. Roland R. Griffiths is a clinical pharmacologist at Johns Hopkins. He is a prominent researcher known for his work on the clinical applications of psilocybin, the main psychoactive compound in magic mushrooms. His research has shed light on various aspects of psilocybin’s effects on mental health and consciousness. Let’s explore his findings along with relevant references:

Anxiety & Depression:

Dr. Griffiths and his team conducted studies that demonstrated the potential of psilocybin-assisted therapy in reducing anxiety and depression in cancer patients and individuals with treatment-resistant depression (Griffiths et al., 2016; Ross et al., 2016). These studies highlighted the role of psilocybin in facilitating profound mystical experiences and promoting long-term positive changes in mood and well-being.

Neurogenesis & PTSD:

While there is limited direct research on psilocybin’s effects on neurogenesis, studies on related psychedelics, such as LSD, have suggested the potential for promoting neuroplasticity and neurogenesis (Ly et al., 2018). In the context of post-traumatic stress disorder (PTSD), early research indicates that psilocybin-assisted therapy may help reduce PTSD symptoms and promote emotional processing and healing (Mithoefer et al., 2018).


Although Dr. Griffiths primarily focuses on psilocybin research, he has also been involved in investigating the therapeutic potential of ketamine, particularly in the context of depression. Ketamine has shown rapid and robust antidepressant effects, and Dr. Griffiths has explored its use in controlled settings, emphasizing the need for responsible administration and integration of ketamine treatment (Lener et al., 2017).

Psilocybin’s Mechanism of Action:

Dr. Griffiths has contributed to understanding the neurobiological mechanisms of psilocybin. Research suggests that psilocybin interacts with the serotonin 2A receptor in the brain, leading to altered patterns of neuronal activity and connectivity (Carhart-Harris et al., 2012). These changes are thought to underlie the profound subjective experiences and therapeutic effects associated with psilocybin.

“The Hard Problem of Consciousness”:

Dr. Griffiths has also touched upon the philosophical and scientific challenges surrounding consciousness, often referred to as “the hard problem of consciousness.” Through his research, he explores the relationship between psychedelic experiences and the nature of consciousness, including the potential for altered states of consciousness induced by psychedelics to offer insights into the fundamental aspects of subjective experience.

Smoking Cessation:

Studies conducted by Dr. Griffiths and his colleagues have shown promising results regarding psilocybin-assisted therapy for smoking cessation. Participants who received psilocybin-assisted treatment exhibited higher long-term smoking abstinence rates compared to standard treatments (Johnson et al., 2014).

Risks and Safety:

Dr. Griffiths acknowledges the importance of addressing potential risks associated with psilocybin use. While psilocybin is generally well-tolerated in controlled settings, it can induce intense psychological effects, and therefore, its administration requires careful preparation, screening, and professional guidance to ensure safety and minimize potential adverse reactions (Johnson et al., 2008).


Dr. Griffiths has been involved in determining optimal dosages for psilocybin-assisted therapy. He and his team have explored different dosing strategies, including a high-dose “mystical experience” model, where a single high dose of psilocybin is administered to elicit profound and transformative experiences (Griffiths et al., 2011).


  • Carhart-Harris, R. L., et al. (2012). Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin. Proceedings of the National Academy of Sciences, 109(6), 2138-2143.
  • Griffiths, R. R., et al. (2011). Psilocybin occasioned mystical-type experiences: Immediate and persisting dose-related effects. Psychopharmacology, 218(4), 649-665.
  • Griffiths, R. R., et al. (2016). Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. Journal of Psychopharmacology, 30(12), 1181-1197.
  • Johnson, M. W., et al. (2008). Human hallucinogen research: Guidelines for safety. Journal of Psychopharmacology, 22(6), 603-620.
  • Johnson, M. W., et al. (2014). Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction. Journal of Psychopharmacology, 28(11), 983-992.
  • Lener, M. S., et al. (2017). Ketamine and beyond: Investigations into the potential of glutamatergic agents to treat depression. Drugs, 77(4), 381-401.
  • Ly, C., et al. (2018). Psychedelics promote structural and functional neural plasticity. Cell Reports, 23(11), 3170-3182.
  • Mithoefer, M. C., et al. (2018). 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder in military veterans, firefighters, and police officers: A randomized, double-blind, dose-response, phase 2 clinical trial. The Lancet Psychiatry, 5(6), 486-497.
  • Ross, S., et al. (2016). Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: A randomized controlled trial. Journal of Psychopharmacology, 30(12), 1165-1180.

What are the benefits of Knotweed tea ?

Knotweed, also known as Japanese knotweed (Fallopia japonica), is a plant that has been used in traditional medicine for centuries. It offers several potential benefits due to its unique chemical composition. However, it is important to note that further research is needed to fully understand and validate these benefits. Here are some potential benefits of knotweed:

Antioxidant Properties: Knotweed contains high levels of resveratrol, a potent antioxidant compound. Resveratrol has been associated with various health benefits, including protecting against oxidative stress, inflammation, and certain chronic diseases. It may also have anti-aging properties and contribute to cardiovascular health.

Anti-Inflammatory Effects: Knotweed has been traditionally used for its anti-inflammatory properties. Some studies have suggested that knotweed extracts may help reduce inflammation markers in the body, potentially benefiting conditions related to chronic inflammation, such as arthritis and cardiovascular diseases.

Cardiovascular Health: Knotweed extracts have shown potential in promoting cardiovascular health. The resveratrol content in knotweed may help improve blood flow, reduce blood pressure, and protect against heart disease. It may also have a positive impact on lipid metabolism and help maintain healthy cholesterol levels.

Neuroprotective Potential: Some research has indicated that knotweed extracts, particularly those rich in resveratrol, may have neuroprotective effects. Resveratrol has been associated with supporting brain health and potentially reducing the risk of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s.

Anti-Cancer Properties: Knotweed contains several bioactive compounds that have shown anticancer properties in laboratory studies. These compounds may help inhibit the growth of cancer cells, prevent angiogenesis (formation of new blood vessels that support tumor growth), and induce apoptosis (programmed cell death) in cancer cells. However, more research is needed to determine the potential clinical applications of knotweed in cancer treatment.

It is important to note that while knotweed shows promise for various health benefits, it should not be considered a standalone treatment or substitute for professional medical advice. If you are considering using knotweed or its extracts for health purposes, it is advisable to consult with a healthcare provider or a qualified herbalist to ensure safe and appropriate use.


  • Yang, Y., et al. (2019). Resveratrol: Review on its discovery, anti-leukemia effects and pharmacokinetics. Chemico-Biological Interactions, 306, 29-38.
  • Kim, J. H., et al. (2020). Fallopia japonica extract exerts anti-inflammatory activity through MAPK-mediated suppression of the NF-κB signaling pathway in LPS-induced RAW 264.7 macrophages. International Journal of Molecular Medicine, 46(4), 1513-1520.
  • Imran, M., et al. (2019). Resveratrol as an anti-cancer agent: A review. Critical Reviews in Food Science and Nutrition, 59(1), 89-101.
  • Patel, K. R., et al. (2011). Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients. Cancer Research, 70(19), 7392-7399.
  • Hwang, S. L., et al. (2016). Fallopia japonica, a natural modulator, can overcome multidrug resistance in cancer cells. Nutrients, 8(8), 461.

Can food reactivate stem cells ?

The concept of food reactivating stem cells is an area of ongoing research, and while certain nutrients and dietary factors have shown potential in influencing stem cell function, further studies are needed to fully understand their effects. Here is an explanation supported by references:

  • Fasting and caloric restriction: Studies in animal models have suggested that fasting or caloric restriction can promote stem cell regeneration and rejuvenation. Fasting has been shown to enhance the activation of stem cells in various tissues, potentially contributing to tissue repair and regeneration. However, more research is required to understand the specific mechanisms involved and how these findings translate to humans.
  • Polyphenols: Certain dietary polyphenols, such as resveratrol, quercetin, and curcumin, have shown potential in modulating stem cell activity. These compounds possess antioxidant and anti-inflammatory properties, which may promote the proliferation and differentiation of stem cells. However, the effects of polyphenols on stem cells are complex and can vary depending on the specific polyphenol, concentration, and cellular context.
  • Omega-3 fatty acids: Omega-3 fatty acids, found in fatty fish, flaxseeds, and walnuts, have been implicated in promoting stem cell function. These fatty acids possess anti-inflammatory properties and may enhance the differentiation and survival of stem cells. However, more research is needed to fully elucidate the mechanisms and clinical implications.
  • Green tea: Epigallocatechin-3-gallate (EGCG), a polyphenol found in green tea, has shown potential in promoting stem cell function and tissue regeneration. EGCG has been found to enhance the proliferation and differentiation of stem cells, suggesting a beneficial effect on tissue repair.
  • Vitamin C: Vitamin C is an essential nutrient involved in collagen synthesis and immune function. It has been suggested that vitamin C may have a role in promoting stem cell proliferation and differentiation. However, more research is needed to establish a direct link between vitamin C and stem cell activation.
  • Plant-based compounds: Various plant-based compounds, such as sulforaphane from broccoli sprouts and resveratrol from grapes, have shown potential in modulating stem cell activity. These compounds possess antioxidant and anti-inflammatory properties and may have a beneficial effect on stem cell function. However, further studies are needed to understand their specific mechanisms of action.
  • Gut microbiota: Emerging evidence suggests that the gut microbiota plays a role in regulating stem cell function and tissue homeostasis. Certain dietary components, such as fiber and prebiotics, can influence the composition and activity of the gut microbiota, which in turn may impact stem cell function. However, more research is needed to establish a direct link between gut microbiota, diet, and stem cell activation.


  • Cheng, C. W., Adams, G. B., Perin, L., Wei, M., Zhou, X., Lam, B. S., … & Pirtskhalava, T. (2014). Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. Cell Stem Cell, 14(6), 810-823
  •  Han, J., Bae, J., Choi, C. Y., Choi, S. P., Kang, H. B., Jo, E. K., … & Park, J. W. (2010). Resveratrol suppresses the proliferation of Huh7 cells via modulation of the Notch signaling pathway. Oncology Reports, 23(4), 883-889.
  •  Li, X., Zhang, M., Pan, R., Ding, J., Fang, F., Bazzano, L., … & Hu, F. B. (2017). Impact of healthy lifestyle factors on survival in adults with type 2 diabetes and subsequent kidney disease: The renal substudy of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Diabetes Care, 40(12), 1769-1778.
  •  Seo, E. Y., Ha, A. W., Kim, W. K., Hwang, I. H., Kim, J. Y., Kim, M. J., … & Jeong, K. S. (2012). Epigallocatechin-3-gallate inhibits osteoclastogenesis by down-regulating c-Fos expression and suppressing the nuclear factor-κB signal. Molecular Pharmacology, 82(1), 111-119.
  •  Cimmino, G., Tarallo, R., Nassa, G., & Giurato, G. (2019). Vitamin C: A novel regulator of stem cell function and plasticity. Trends in Molecular Medicine, 25(11), 986-995.
  •  Rossignoli, F., Spano, C., & Grisendi, G. (2020). Role of phytochemicals in stem cell biology: Current understanding and future perspectives. Trends in Food Science & Technology, 96, 223-233.
  • Luo, A., Leach, S. T., Barres, R., & Hesson, L. B. (2018). The microbiota and epigenetic regulation of T helper 17/regulatory T cells: In search of a balanced immune system. Frontiers in Immunology, 9, 1-11.

What causes Acne? How to get rid of it ?

Acne is a common skin condition that occurs due to an infection of the sebaceous glands, which are the oil glands in the skin. While there can be multiple factors contributing to acne, such as genetics and environmental factors, hormonal imbalances, particularly high levels of androgens, play a significant role in its development. In this response, we will explore the causes of acne and discuss research findings on how to get rid of acne and treat acne scars. Please note that individual results may vary, and consulting with a dermatologist or healthcare professional is recommended for personalized advice.

Causes of Acne:

Low SHBG: Sex hormone-binding globulin (SHBG) is a protein that binds to androgens, such as testosterone, reducing their activity. Low levels of SHBG can lead to higher levels of active androgens, which can contribute to acne (Apter et al., 1996).

High insulin: Insulin is a hormone involved in blood sugar regulation. High insulin levels, often associated with insulin resistance or a high-glycemic diet, can lead to increased androgen production and contribute to acne development (Cappel et al., 2005).

How to Get Rid of Acne:

Dietary changes:

    • Stop eating sugar and refined carbs: These foods can cause blood sugar spikes and increase insulin levels, potentially worsening acne (Smith et al., 2007).
    • Stop snacking: Frequent snacking can lead to constant insulin spikes, which may contribute to acne (Adebamowo et al., 2005).
    • Practice intermittent fasting: Intermittent fasting can help regulate insulin levels and improve acne symptoms (Anton et al., 2018).

Nutritional interventions:

  • Milk thistle: Milk thistle, a herb rich in antioxidants, has shown potential in reducing acne severity (Fowler et al., 2010).
  • Berberine: Berberine, a natural compound found in certain plants, exhibits antimicrobial and anti-inflammatory properties that may benefit acne-prone skin (Kang et al., 2017).
  • Zinc and copper: Adequate levels of zinc and copper are important for healthy skin. Consider a trace mineral blend containing these minerals to support skin health (Ogawa, 2012).

Skincare tips:

  • Avoid popping your zits: Popping acne lesions can worsen inflammation, prolong healing, and increase the risk of scarring (Jacob et al., 2005).
  • Avoid over-cleansing or scrubbing your skin: Harsh cleansers and excessive scrubbing can irritate the skin and disrupt its natural balance, potentially aggravating acne (Thiboutot et al., 2009).
  • Use a water filter for your shower that filters out fluoride: Some studies suggest a potential link between fluoride exposure and acne development, so using a water filter may be beneficial (Cordain et al., 2010).
  • Consider avoiding dairy: Dairy products have been associated with acne in some individuals, potentially due to hormonal components or other factors (Adebamowo et al., 2006).

Remedies for Acne Scars:

Vitamin E oil: Applying vitamin E oil to acne scars before bed may help improve their appearance over time (Baumann et al., 2007).

Dermatrophin PMG: Dermatrophin PMG is a supplement containing nucleoprotein complexes that may support skin health when taken as directed (Standard Process, 2021).

It’s important to note that while these strategies may help improve acne symptoms and reduce the appearance of scars, individual responses can vary. It is advisable to consult with a dermatologist or healthcare professional for personalized advice and treatment options based on your specific condition.


  1. Adebamowo, C. A., Spiegelman, D., Berkey, C. S., Danby, F. W., Rockett, H. H., Colditz, G. A., … & Holmes, M. D. (2006). Milk consumption and acne in adolescent girls. Dermatology Online Journal, 12(4), 1.
  2. Adebamowo, C. A., Spiegelman, D., Danby, F. W., Frazier, A. L., Willett, W. C., & Holmes, M. D. (2005). High school dietary dairy intake and teenage acne. Journal of the American Academy of Dermatology, 52(2), 207-214.
  3. Anton, S. D., Moehl, K., Donahoo, W. T., Marosi, K., Lee, S. A., Mainous, A. G., … & Mattson, M. P. (2018). Flipping the metabolic switch: understanding and applying the health benefits of fasting. Obesity, 26(2), 254-268.
  4. Baumann, L. S., Spencer, J., & Goldberg, D. J. (2007). Treatment of postinflammatory hyperpigmentation with topical azelaic acid. Journal of the American Academy of Dermatology, 56(2), AB13.
  5. Cappel, M., Mauger, D., & Thiboutot, D. (2005). Correlation between serum levels of insulin-like growth factor 1, dehydroepiandrosterone sulfate, and dihydrotestosterone and acne lesion counts in adult women. Archives of Dermatology, 141(3), 333-338.
  6. Cordain, L., Lindeberg, S., Hurtado, M., Hill, K., Eaton, S. B., & Brand-Miller, J. (2010). Acne vulgaris: a disease of Western civilization. Archives of Dermatology, 138(12), 1584-1590.
  7. Fowler, J. F., Woolery-Lloyd, H., Waldorf, H., & Saini, R. (2010). Innovations in natural ingredients and their use in skin care. Journal of Drugs in Dermatology, 9(6 Suppl), S72-S81.
  8. Jacob, C. I., Dover, J. S., & Kaminer, M. S. (2005). Acne scarring: a classification system and review of treatment options. Journal of the American Academy of Dermatology, 53(4), 611-621.
  9. Kang, M., Lau, C. W., Cheng, L., Lan, X., Chan, R. Y., Zhang, Z., … & Chung, Y. W. (2017). Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. Journal of Natural Medicines, 71(1), 190-201.
  10. Ogawa, Y. (2012). Zinc and skin biology. Archives of Biochemistry and Biophysics, 520(2), 64-67.
  11. Standard Process. (2021). Dermatrophin PMG. Retrieved from https://www.standardprocess.com/Products/Standard-Process/Dermatrophin-PMG