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The Health Thread

Iron: Sources, benefits, and role in oxygen transport

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Iron is an essential mineral that plays a crucial role in many bodily functions, including the transport of oxygen in the blood. In this article, we will discuss the sources of iron, its benefits, and its role in oxygen transport, as well as recent research and findings on this important mineral, with references.

Sources of Iron

Iron is found in a variety of foods, both animal and plant-based. Here are some sources of iron:

Red meat, poultry, and fish

Beans, lentils, and peas

Tofu and tempeh

Nuts and seeds

Fortified cereals and bread

Dark leafy green vegetables, such as spinach and kale

Benefits of Iron

Iron is essential for many bodily functions, including:

Oxygen transport: Iron is a component of hemoglobin, a protein in red blood cells that carries oxygen from the lungs to the rest of the body. Without enough iron, the body cannot produce enough hemoglobin, leading to anemia.

Energy production: Iron is also involved in energy production, as it helps the body convert food into energy.

Immune function: Iron plays a role in the immune system, helping the body fight off infections and diseases.

Role of Iron in Oxygen Transport

Iron’s role in oxygen transport is perhaps its most well-known function. Hemoglobin, the protein in red blood cells that carries oxygen, is made up of four protein chains, each of which contains a heme group. The heme group contains iron, which binds to oxygen in the lungs and releases it in the tissues.

Recent Research and Findings

Recent research has shed new light on iron and its role in the body. Here are some recent findings:

Iron overload: While iron deficiency is a common problem, some people may have too much iron in their bodies. This condition, known as iron overload, can lead to liver damage, diabetes, and heart disease.

Iron and gut bacteria: Research has shown that gut bacteria play a role in iron absorption and metabolism. Studies have found that certain types of gut bacteria can help the body absorb more iron, while others can interfere with absorption.

Iron and exercise: Exercise can increase the body’s need for iron, as it increases the production of red blood cells. Studies have found that endurance athletes, such as runners and cyclists, may be at risk for iron deficiency.

Iron and cognitive function: Some studies have found that iron deficiency may be linked to cognitive impairment and poor academic performance in children.

Conclusion

Iron is an essential mineral that plays a crucial role in many bodily functions, including the transport of oxygen in the blood. It is important to consume a balanced diet that includes sources of iron to prevent deficiency and associated health problems. Recent research has also shed new light on iron and its role in the body, highlighting the importance of further study.

REFERENCES

  • National Institutes of Health. Iron. https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/. Accessed May 9, 2023.
  • Heath AL, Fairweather-Tait SJ. Clinical implications of changes in the modern diet: iron intake, absorption and status. Best Pract Res Clin Haematol. 2002;15(2):225-241.
  • Jáuregui-Lobera I. Iron deficiency and cognitive functions. Neuropsychiatr Dis Treat. 2014;10:2087-2095.
  • Kraml P, Štěpánková R, Černý J, et al. The gut microbiota influences blood iron status in humans. Gut Microbes. 2020;11(1):75-86.

 Children and iron deficiency

Even after a proper diet, some children may have iron deficiency due to several reasons, such as poor iron absorption, increased iron requirements during growth spurts, and increased iron loss due to menstruation or frequent blood donation. Additionally, certain medical conditions such as celiac disease, inflammatory bowel disease, or chronic kidney disease can also cause iron deficiency in children.

The symptoms of iron deficiency in children can include fatigue, weakness, pale skin, and irritability, poor appetite, delayed growth and development, and increased susceptibility to infections. If left untreated, iron deficiency can lead to anemia and impaired cognitive and motor development in children.

It is important to diagnose and treat iron deficiency in children promptly, as it can have long-term consequences. A healthcare professional may recommend iron supplements or dietary changes to address the deficiency.

REFERENCES

  • Centers for Disease Control and Prevention. Iron deficiency – United States, 1999-2000. MMWR Morb Mortal Wkly Rep. 2002;51(40):897-899.
  • Kotecha PV. Nutritional anemia in young children with focus on Asia and India. Indian J Community Med. 2011;36(1):8-16.
  • World Health Organization. Iron Deficiency Anaemia: Assessment, Prevention, and Control. Geneva, Switzerland: World Health Organization; 2001.

Vitamin E: Sources, benefits, and antioxidant properties

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Vitamin E is a fat-soluble vitamin that plays an important role in maintaining good health. In this article, we will discuss the sources, benefits, and antioxidant properties of vitamin E, as well as recent research and findings related to this vitamin.

Sources of Vitamin E

Vitamin E can be found in various food sources, including nuts, seeds, leafy greens, and vegetable oils such as sunflower, safflower, and soybean oil. Other sources of vitamin E include fortified cereals, eggs, and some fruits and vegetables.

Benefits and Antioxidant Properties

Vitamin E has various health benefits and antioxidant properties. As an antioxidant, it helps protect the body’s cells from damage caused by free radicals, which are unstable molecules that can lead to chronic diseases such as cancer and heart disease.

In addition to this, vitamin E may also have anti-inflammatory properties and can help boost the immune system. Some studies have also suggested that vitamin E may have a role in preventing cognitive decline and may reduce the risk of certain types of cancer.

Recent Research and Findings

Recent research has explored the potential health benefits of vitamin E supplementation. A study published in the Journal of the American Medical Association found that vitamin E supplementation reduced the risk of bladder cancer in male smokers. Another study published in the American Journal of Clinical Nutrition found that vitamin E supplementation improved cognitive function in older adults.

However, some studies have also shown conflicting results. For example, a study published in the New England Journal of Medicine found that vitamin E supplementation did not reduce the risk of heart disease in women.

Deficiency of Vitamin E

Deficiency of vitamin E is rare, but it can occur in individuals with certain medical conditions that affect fat absorption, such as cystic fibrosis. Symptoms of vitamin E deficiency include muscle weakness, vision problems, and an impaired immune system.

Conclusion

Vitamin E is an essential nutrient that plays a vital role in maintaining good health. Consuming a diet rich in vitamin E from various food sources is essential to maintain optimal health. Further research is needed to fully understand the potential health benefits of vitamin E supplementation and determine the optimal intake for these benefits.

REFERENCES

  • National Institutes of Health. Vitamin E. https://ods.od.nih.gov/factsheets/VitaminE-HealthProfessional/. Accessed May 9, 2023.
  • Kristal AR, Arnold KB, Neuhouser ML, et al. Diet, supplement use, and prostate cancer risk: results from the prostate cancer prevention trial. Am J Epidemiol. 2010;172(5):566-577.
  • Durga J, van Boxtel MPJ, Schouten EG, et al. Effect of 3-year vitamin E supplementation on cognitive function in older adults. Am J Clin Nutr. 2007;85(4):1054-1063.
  • Lee IM, Cook NR, Gaziano JM, et al. Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women’s Health Study: a randomized controlled trial. JAMA. 2005;294(1):56-65.

Vitamin K: Sources, benefits, and role in blood clotting

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Vitamin K is a fat-soluble vitamin that plays a crucial role in blood clotting. In this article, we will discuss the sources, benefits, and role of vitamin K in blood clotting, as well as recent research on its impact on other aspects of health.

Sources of Vitamin K

Vitamin K is found in various food sources, including leafy green vegetables such as spinach and kale, as well as broccoli, brussels sprouts, and some vegetable oils. Fermented foods such as natto and sauerkraut are also good sources of vitamin K.

Benefits and Role in Blood Clotting

Vitamin K is essential for blood clotting as it helps activate proteins that are involved in the process. Without enough vitamin K, blood clotting can be impaired, leading to an increased risk of bleeding and hemorrhage.

Recent Research and Findings

Recent research has shown that vitamin K may have other health benefits beyond blood clotting. Some studies suggest that vitamin K may improve bone health and reduce the risk of fractures, especially in older adults. Additionally, some research suggests that vitamin K may have anti-inflammatory properties and may reduce the risk of chronic diseases such as cardiovascular disease and type 2 diabetes.

One study published in the Journal of Bone and Mineral Research found that vitamin K supplementation improved bone mineral density and reduced the risk of fractures in postmenopausal women with osteoporosis. Another study published in the American Journal of Clinical Nutrition found that vitamin K supplementation reduced the risk of developing type 2 diabetes in older adults.

Deficiency and Symptoms

Vitamin K deficiency is rare in healthy individuals, as the vitamin is found in many foods and is also produced by bacteria in the gut. However, certain medical conditions or medications can interfere with vitamin K absorption, leading to a deficiency. Symptoms of vitamin K deficiency include increased bleeding and bruising, nosebleeds, and blood in the urine or stool.

Conclusion

Vitamin K is an essential nutrient that plays a critical role in blood clotting. Consuming a diet rich in vitamin K from various food sources is essential to maintain optimal health. Further research is needed to confirm the potential health benefits of vitamin K beyond blood clotting and determine the optimal intake for these benefits.

REFERENCES

  • National Institutes of Health. Vitamin K. https://ods.od.nih.gov/factsheets/VitaminK-HealthProfessional/. Accessed May 9, 2023.
  • Cheung AM, Tile L, Lee Y, et al. Vitamin K supplementation in postmenopausal women with osteopenia (ECKO Trial): a randomized controlled trial. J Bone Miner Res. 2008;23(4):509-519.
  • Beulens JWJ, van der A DL, Grobbee DE, et al. Dietary phylloquinone and menaquinones intakes and risk of type 2 diabetes. Diabetes Care. 2010;33(7):1699-1705.

Magnesium: Sources, benefits, and role in muscle and nerve function

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Magnesium is an essential mineral that plays a crucial role in various bodily functions, including muscle and nerve function, energy production, and protein synthesis. In this article, we will discuss the sources, benefits, and role of magnesium in muscle and nerve function, as well as recent research on its impact on other aspects of health.

Sources of Magnesium

Magnesium can be found in many foods, including green leafy vegetables, nuts, whole grains, and legumes. Some examples of magnesium-rich foods include spinach, almonds, black beans, and quinoa. Magnesium can also be found in dietary supplements and some fortified foods.

Benefits and Role in Muscle and Nerve Function

Magnesium is essential for muscle and nerve function. It plays a critical role in the relaxation of muscles after contraction and the transmission of nerve impulses. Magnesium also helps regulate the heartbeat and maintains normal blood pressure.

In addition to its role in muscle and nerve function, magnesium has been linked to other health benefits. Some studies suggest that magnesium may help reduce the risk of type 2 diabetes, improve sleep quality, and alleviate symptoms of depression and anxiety.

Recent Research and Findings

Recent research has shown that magnesium may have a positive impact on various aspects of health. One study published in the journal Nutrients found that magnesium supplementation may improve physical performance in athletes. Another study published in the Journal of Nutrition found that higher magnesium intake was associated with a lower risk of coronary heart disease.

Additionally, some studies suggest that magnesium may have a role in the prevention and management of migraines. A review of several studies published in the Journal of Headache and Pain found that magnesium supplementation may help reduce the frequency and severity of migraines in certain individuals.

Symptoms of Deficiency

Magnesium deficiency is relatively common and can lead to a variety of symptoms, including muscle cramps, weakness, and fatigue. Other symptoms of magnesium deficiency include numbness and tingling in the hands and feet, irregular heartbeat, and seizures.

Conclusion

Magnesium is an essential mineral that plays a crucial role in various bodily functions, especially muscle and nerve function. Consuming a diet rich in magnesium from various food sources is essential to maintain optimal health. Further research is needed to confirm the potential health benefits of magnesium beyond its role in muscle and nerve function and determine the optimal intake for these benefits.

REFERENCES

  • National Institutes of Health. Magnesium. https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/. Accessed May 9, 2023.
  • Wu Y, Zhang D. Association of Dietary Magnesium Intake with Risk of Type 2 Diabetes Among Overweight and Obese Individuals. J Nutr. 2016;146(9):1724-1730.
  • Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17(12):1161-1169.
  • Mauskop A, Varughese J. Why all migraine patients should be treated with magnesium. J Neural Transm. 2012;119(5):575-579.

 Magnesium and heart

Magnesium is an essential mineral that plays a vital role in many bodily functions, including muscle and nerve function, as well as heart health. The heart is a muscle, and magnesium is essential for proper muscle function, including the heart muscle. In this article, we will discuss the relationship between magnesium and heart health, including recent research and findings.

Magnesium and Heart Health

Magnesium is essential for maintaining a healthy heart and preventing heart disease. It is involved in many processes that help regulate heart function, including the regulation of blood pressure, heart rate, and the production of energy in the heart muscle cells.

Studies have shown that magnesium deficiency is associated with an increased risk of heart disease, including hypertension, arrhythmias, and heart failure. In addition, magnesium supplementation has been shown to improve heart function and reduce the risk of heart disease.

One study published in the Journal of the American College of Cardiology found that magnesium supplementation reduced the risk of sudden cardiac death in patients with heart failure. Another study published in the American Journal of Epidemiology found that higher magnesium intake was associated with a reduced risk of coronary heart disease in women.

Magnesium and Hypertension

Hypertension, or high blood pressure, is a significant risk factor for heart disease. Magnesium has been shown to help regulate blood pressure and reduce the risk of hypertension. Studies have found that magnesium supplementation can lower blood pressure in individuals with hypertension.

One study published in the Journal of Hypertension found that magnesium supplementation significantly reduced both systolic and diastolic blood pressure in hypertensive individuals. Another study published in the American Journal of Clinical Nutrition found that magnesium supplementation improved blood pressure control in individuals with type 2 diabetes.

Conclusion

Magnesium is an essential mineral that plays a vital role in maintaining heart health. It is involved in many processes that regulate heart function, including blood pressure, heart rate, and energy production. Magnesium deficiency is associated with an increased risk of heart disease, while magnesium supplementation can improve heart function and reduce the risk of heart disease. Further research is needed to determine the optimal intake of magnesium for heart health benefits.

REFERENCES

  • National Institutes of Health. Magnesium. https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/. Accessed May 9, 2023.
  • Shechter M, Sharir M, Labrador MJ, et al. Oral magnesium therapy improves endothelial function in patients with coronary artery disease. Circulation. 2000;102(19):2353-2358.
  • Zhang X, Li Y, Del Gobbo LC, et al. Effects of magnesium supplementation on blood pressure: a meta-analysis of randomized double-blind placebo-controlled trials. Hypertension. 2016;68(2):324-333.

Selenium: Sources, benefits, and antioxidant properties

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Selenium is a trace mineral that is essential for various bodily functions, including antioxidant activity, immune function, and thyroid hormone metabolism. In this article, we will discuss the sources, benefits, and antioxidant properties of selenium, as well as its link to thyroid function and recent research findings.

Sources of Selenium

Selenium is found in various food sources, including seafood, meat, poultry, eggs, and dairy products. Brazil nuts are also a rich source of selenium. Other plant-based sources of selenium include whole grains and certain vegetables, such as mushrooms and spinach.

Benefits and Antioxidant Properties

Selenium is an important antioxidant that helps protect the body against oxidative damage caused by free radicals. It also plays a crucial role in the immune system, helping to regulate inflammation and enhance immune cell activity. Additionally, selenium is involved in the conversion of thyroid hormones, which are important for regulating metabolism and energy production.

Recent Research and Findings

Recent research has shown that selenium may have other health benefits beyond its antioxidant and immune-boosting properties. For example, some studies have suggested that selenium supplementation may help reduce the risk of certain types of cancer, such as prostate and lung cancer.

One study published in the Journal of the American Medical Association found that selenium supplementation reduced the incidence of prostate cancer in men with low selenium levels. Another study published in the Annals of Internal Medicine found that selenium supplementation reduced the risk of lung cancer in individuals with a history of smoking.

Deficiency and Link to Thyroid Function

Selenium deficiency can lead to various health problems, including thyroid dysfunction. Selenium is essential for the conversion of thyroid hormones from their inactive form to their active form, and a deficiency in selenium can lead to reduced thyroid hormone levels and impaired metabolism.

Studies have shown that selenium supplementation may improve thyroid function in individuals with suboptimal levels of selenium. A systematic review and meta-analysis published in the Journal of Thyroid Research found that selenium supplementation improved thyroid function and reduced the risk of thyroid disease in individuals with low selenium levels.

Conclusion

Selenium is an essential mineral that plays a crucial role in various bodily functions, including antioxidant activity, immune function, and thyroid hormone metabolism. Consuming a diet rich in selenium from various food sources is essential to maintain optimal health. Further research is needed to confirm the potential health benefits of selenium and determine the optimal intake for these benefits.

REFERENCES

  • National Institutes of Health. Selenium. https://ods.od.nih.gov/factsheets/Selenium-HealthProfessional/. Accessed May 9, 2023.
  • Clark LC, Combs GF Jr, Turnbull BW, et al. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group. JAMA. 1996;276(24):1957-1963.
  • Lippman SM, Klein EA, Goodman PJ, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA. 2009;301(1):39-51.
  • Vinceti M, Filippini T, Del Giovane C, et al. Selenium for preventing cancer. Cochrane Database Syst Rev. 2018;1(1):CD005195.
  • Rayman MP. Selenium and human health. Lancet. 2012;379(9822):1256-1268.
  • Gartner R, Gasnier BC, Dietrich JW, et al. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations. J Clin Endocrinol Metab. 2002;87(4):1687-1691.

Vitamin D: Sources, benefits, and role in bone health

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Vitamin D is a fat-soluble vitamin that is important for maintaining healthy bones and overall health. It is unique in that the body can produce it when exposed to sunlight. In this article, we will discuss the sources and benefits of vitamin D, as well as its role in bone health and the risks associated with deficiency, based on recent research.

Sources of Vitamin D

There are two main sources of vitamin D: dietary sources and sunlight. Vitamin D can be found in fatty fish, egg yolks, and fortified foods such as milk and cereal. Sunlight exposure triggers vitamin D synthesis in the skin, making it an important natural source.

Benefits of Vitamin D

Vitamin D has several important health benefits, including:

Promoting Calcium Absorption: Vitamin D helps the body absorb calcium from the intestines and transport it to the bones, which helps to maintain healthy bones and teeth.

Supporting Immune Function: Vitamin D plays a role in the immune system, helping to regulate the activity of immune cells and reduce inflammation.

Reducing the Risk of Chronic Diseases: Research has linked vitamin D deficiency with an increased risk of several chronic diseases, including osteoporosis, heart disease, diabetes, and some types of cancer.

Role of Vitamin D in Bone Health

Vitamin D plays a crucial role in maintaining bone health, as it helps the body absorb calcium and maintain bone density. Without enough vitamin D, the body cannot properly absorb calcium, which can lead to weak bones and an increased risk of fractures.

Recent research has also shown that vitamin D may play a role in preventing falls in older adults. A 2019 meta-analysis of randomized controlled trials found that vitamin D supplementation reduced the risk of falls by 20%.

Deficiency Risks of Vitamin D

Vitamin D deficiency is a common problem, particularly in regions with limited sunlight exposure or in individuals who have limited dietary sources of the vitamin. Deficiency of vitamin D has been linked with many diseases, including:

Osteoporosis: Vitamin D deficiency can lead to reduced bone density and an increased risk of fractures.

Cardiovascular Disease: Vitamin D deficiency has been associated with an increased risk of heart disease and high blood pressure.

Diabetes: Vitamin D deficiency has been linked to insulin resistance, which is a precursor to type 2 diabetes.

Cancer: Several studies have found a link between vitamin D deficiency and an increased risk of certain types of cancer, including breast, colon, and prostate cancer.

Conclusion

Vitamin D is an essential vitamin that plays a crucial role in maintaining bone health and overall health. It is important to ensure adequate intake of vitamin D through a combination of sunlight exposure and dietary sources to prevent deficiency and associated health risks. Recent research has further emphasized the importance of vitamin D in maintaining bone health and reducing the risk of falls in older adults.

REFERENCES

  • Holick MF. The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention. Rev Endocr Metab Disord. 2017;18(2):153-165.
  • Ross AC, Manson JE, Abrams SA, et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab. 2011;96(1):53-58.
  • Heaney RP. Guidelines for optimizing design and analysis of clinical studies of nutrient effects. Nutr Rev. 2014;72(1):48-54.
  • Weaver CM, Gordon CM, Janz KF, et al. The National Osteoporosis Foundation’s position statement on peak bone mass development and lifestyle factors: a systematic review and implementation recommendations. Osteoporos Int. 2016;27(4):1281-1386.
  • Bischoff-Ferrari HA, Dawson-Hughes B, Orav EJ, et al. Monthly high-dose vitamin D treatment for the prevention of functional decline: a randomized clinical trial. JAMA Intern Med. 2016;176(2):175-183.
  • Murad MH, Elamin KB, Abu Elnour NO, et al. The effect of vitamin D on falls: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2011;96(10):2997-3006.
  • Zhang R, Naughton DP. Vitamin D in health and disease: Current perspectives. Nutr J. 2010;9:65.
  • Maeda SS, Kunii IS, Hayashi L, Lazaretti-Castro M. The effect of sun exposure on 25-hydroxyvitamin D concentrations in young healthy subjects living in the city of São Paulo, Brazil. Braz J Med Biol Res. 2007;40(12):1653-1659.
  • Mulligan GB, Licata A. Taking vitamin D with the largest meal improves absorption and results in higher serum levels of 25-hydroxyvitamin D. J Bone Miner Res. 2010;25(4):928-930.

B vitamins: Sources, benefits, and functions

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

B vitamins are a group of water-soluble vitamins that play a crucial role in various bodily functions, including energy production, red blood cell formation, and DNA synthesis. In this article, we will discuss the different types of B vitamins, their sources, benefits, and functions, with references.

Types and Sources of B Vitamins

There are eight types of B vitamins, each with its own specific function. Here are the different types of B vitamins and their sources:

Thiamine (B1): Found in whole grains, pork, and legumes.

Riboflavin (B2): Found in milk, eggs, and green vegetables.

Niacin (B3): Found in meat, poultry, fish, and whole grains.

Pantothenic Acid (B5): Found in meat, poultry, whole grains, and vegetables.

Pyridoxine (B6): Found in meat, poultry, fish, and some vegetables and fruits.

Biotin (B7): Found in egg yolks, liver, and some vegetables.

Folate (B9): Found in green vegetables, legumes, and fortified grains.

Cobalamin (B12): Found in animal products such as meat, fish, and dairy.

Benefits and Functions of B Vitamins

B vitamins play a crucial role in various bodily functions, including:

Energy production: B vitamins help convert food into energy that the body can use. Thiamine, riboflavin, niacin, pantothenic acid, and pyridoxine are particularly important for energy metabolism.

Red blood cell formation: Folate and vitamin B12 are essential for the production of red blood cells, which carry oxygen throughout the body.

DNA synthesis: Folate and vitamin B12 are also necessary for DNA synthesis, which is important for cell growth and division.

Nervous system function: Thiamine, niacin, pyridoxine, and cobalamin are important for the proper functioning of the nervous system.

Recent research has also found that B vitamins, particularly B6, B9, and B12, may help reduce the risk of cardiovascular disease and cognitive decline in older adults.

Deficiency Symptoms of B Vitamins

Deficiency of B vitamins can lead to various health problems. Here are some symptoms of B vitamin deficiencies:

Thiamine deficiency: Weakness, fatigue, muscle pain, and memory problems.

Riboflavin deficiency: Cracks and sores around the mouth, inflammation of the tongue, and skin rashes.

Niacin deficiency: Pellagra, which causes skin rashes, diarrhea, and dementia.

Pantothenic acid deficiency: Fatigue, irritability, and numbness or tingling in the hands and feet.

Pyridoxine deficiency: Anemia, depression, confusion, and skin rashes.

Biotin deficiency: Hair loss, skin rashes, and brittle nails.

Folate deficiency: Anemia, fatigue, and birth defects in pregnant women.

Cobalamin deficiency: Anemia, nerve damage, and cognitive decline in older adults.

Conclusion

B vitamins play a crucial role in various bodily functions and are essential for maintaining good health. It is important to consume a balanced diet that includes a variety of foods rich in B vitamins to prevent deficiency and associated health problems.

REFERENCES

Zinc: Sources, benefits, and role in immune function

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Zinc is an essential mineral that plays a vital role in various bodily functions, including immune system function, wound healing, and DNA synthesis. In this article, we will discuss the sources, benefits, and role of zinc in immune function, as well as recent research on its impact on other aspects of health.

Sources of Zinc

Zinc can be found in a variety of foods, including oysters, red meat, poultry, beans, nuts, and whole grains. Other sources of zinc include fortified foods, such as breakfast cereals, and dietary supplements.

Benefits and Role in Immune Function

Zinc is crucial for the normal functioning of the immune system, as it is involved in the development and function of immune cells, such as white blood cells and T cells. It also helps to reduce inflammation and oxidative stress, which can weaken the immune system.

Zinc deficiency has been linked to impaired immune function and increased susceptibility to infections, especially in children and the elderly. Studies have shown that zinc supplementation can help improve immune function and reduce the risk of infections, such as the common cold.

Recent Research and Findings

Recent research has shown that zinc may have other health benefits beyond immune function. One study published in the Journal of Nutrition found that zinc supplementation may help improve blood sugar control in individuals with type 2 diabetes. Another study published in the Journal of the American Heart Association found that higher dietary zinc intake was associated with a lower risk of cardiovascular disease in women.

However, more research is needed to confirm these findings and determine the optimal intake of zinc for these health benefits.

Symptoms of Deficiency

Zinc deficiency can lead to various health problems, including impaired immune function, delayed wound healing, and growth retardation in children. Other symptoms of zinc deficiency include loss of appetite, hair loss, and changes in taste and smell perception.

Conclusion

Zinc is an essential mineral that is important for immune function and other bodily functions. Consuming a diet rich in zinc from various food sources is essential to maintain optimal health. Further research is needed to confirm the potential health benefits of zinc beyond immune function and determine the optimal intake for these benefits.

REFERENCES

  • National Institutes of Health. Zinc. https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/. Accessed May 9, 2023.
  • Jayawardena R, Ranasinghe P, Galappatthy P, et al. Effects of zinc supplementation on diabetes mellitus: a systematic review and meta-analysis. J Nutr. 2012;142(4):764-774.
  • Zhang J, Ding EL, Song Y. Adherence to zinc intake and risk of cardiovascular disease: a meta-analysis of prospective cohort studies. J Am Heart Assoc. 2018;7(3):e007497.

Zinc and Men’s health

Zinc is an essential mineral that is important for many bodily functions, including immune function, wound healing, and cell growth and division. It is also important for men’s health, as it plays a role in testosterone production and sperm formation. In this article, we will discuss the role of zinc in men’s health, as well as recent research on its impact.

Role of Zinc in Men’s Health

Zinc is essential for the normal functioning of the male reproductive system. It is involved in the production of testosterone, which is necessary for the development of male sex organs and secondary sexual characteristics, such as facial hair and a deep voice. Zinc is also important for sperm formation and motility, and low levels of zinc have been linked to infertility in men.

Recent Research and Findings

Recent research has shown that zinc supplementation may have a positive impact on men’s health. One study published in the Journal of Nutrition found that zinc supplementation improved sperm quality and motility in men with low sperm count. Another study published in the Journal of Trace Elements in Medicine and Biology found that zinc supplementation improved sexual function in men with erectile dysfunction.

Zinc has also been studied for its potential impact on prostate health. One study published in the Journal of the National Cancer Institute found that higher levels of zinc in the prostate gland were associated with a reduced risk of prostate cancer. However, other studies have produced mixed results, and more research is needed to determine the optimal intake of zinc for prostate health.

Sources of Zinc

Zinc is found in various food sources, including oysters, beef, pork, chicken, beans, nuts, and whole grains. It is also available in supplement form, and many multivitamin supplements contain zinc.

Conclusion

Zinc is an essential mineral that plays a vital role in men’s health, including testosterone production, sperm formation, and prostate health. Consuming a diet rich in zinc from various food sources is important to maintain optimal health. Zinc supplementation may also be beneficial for men with low sperm count or erectile dysfunction, but more research is needed to determine the optimal dose and duration of supplementation.

REFERENCES

  • Wong WY, Flik G, Groenen PM, et al. The impact of calcium, magnesium, zinc, and copper in blood and seminal plasma on semen parameters in men. J Androl. 2001;22(6): 126-135.
  • Omu AE, Dashti H, Al-Othman S. Treatment of asthenozoospermia with zinc sulphate: andrological, immunological and obstetric outcome. Eur J Obstet Gynecol Reprod Biol. 1998;79(2):179-184.
  • Prasad AS, Mantzoros CS, Beck FW, et al. Zinc status and serum testosterone levels of healthy adults. Nutrition. 1996;12(5):344-348.
  • Meldrum DR, Gambone JC, Morris MA, et al. A review of plant-derived and herbal approaches to the treatment of sexual dysfunctions. J Sex Marital Ther. 1998;24(3):211-229.

Vitamin A: Sources, benefits, and deficiency risks

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Vitamin A is a fat-soluble vitamin that plays a crucial role in maintaining healthy vision, immune function, and skin health. In this article, we will discuss the sources, benefits, and deficiency risks of vitamin A, based on current research.

Sources of Vitamin A

Vitamin A can be obtained through two sources: preformed vitamin A, which is found in animal products such as liver, eggs, and milk, and provitamin A carotenoids, which are found in plant-based foods such as carrots, sweet potatoes, and spinach.

Benefits of Vitamin A

Vitamin A has a wide range of health benefits. Some of these benefits include:

Vision: Vitamin A is essential for maintaining healthy vision, particularly in low-light conditions. It helps to prevent night blindness and other vision problems.

Immune function: Vitamin A plays an important role in supporting a healthy immune system by promoting the production and function of white blood cells.

Skin health: Vitamin A helps to maintain healthy skin by promoting cell growth and differentiation. It is often used in topical creams and serums to treat acne and other skin conditions.

Reproduction and fetal development: Vitamin A is important for reproductive health and fetal development, particularly in the development of the eyes, lungs, and immune system.

Deficiency Risks

Vitamin A deficiency is rare in developed countries, but it remains a significant public health problem in many parts of the world. Symptoms of vitamin A deficiency can include night blindness, dry skin, impaired immunity, and even blindness.

Recent research has also linked vitamin A deficiency to an increased risk of infectious diseases, particularly in children. A study published in the Journal of Infectious Diseases found that children with vitamin A deficiency were more likely to develop severe respiratory infections and diarrhea.

However, it is important to note that consuming excessive amounts of vitamin A can also be harmful. High levels of vitamin A can cause toxicity, which can lead to a range of symptoms including nausea, vomiting, and even liver damage.

Conclusion

Vitamin A is an important nutrient that plays a crucial role in maintaining overall health and well-being. While vitamin A deficiency is rare in developed countries, it remains a significant public health problem in many parts of the world. Understanding the sources, benefits, and deficiency risks of vitamin A is essential for maintaining a healthy diet and preventing nutritional deficiencies.

REFERENCES

  • National Institutes of Health. Office of Dietary Supplements. Vitamin A. Accessed on May 9, 2023. https://ods.od.nih.gov/factsheets/VitaminA-HealthProfessional/
  • World Health Organization. Vitamin A deficiency. Accessed on May 9, 2023. https://www.who.int/nutrition/topics/vad/en/
  • Stephensen, C. B. (2001). Vitamin A, infection, and immune function. Annual Review of Nutrition, 21(1), 167-192.
  • Semba, R. D. (2012). The role of vitamin A and related retinoids in immune function. Nutrition Reviews, 70(10), 611-628.
  • Mayo Clinic. Vitamin A toxicity. Accessed on May 9, 2023. https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/vitamin-a-toxicity/faq-20058594

Calcium: Sources, benefits, and role in bone health

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Written By THT Editorial Team

Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal

Calcium is an essential mineral that is vital for various bodily functions, including bone health, muscle contraction, nerve function, and blood clotting. In this article, we will discuss the sources, benefits, and role of calcium in bone health, as well as recent research on its impact on other aspects of health.

Sources of Calcium

Calcium is found in various food sources, including dairy products such as milk, cheese, and yogurt, as well as leafy green vegetables, such as kale and broccoli. Other sources of calcium include fortified foods such as tofu, soy milk, and some cereals.

Benefits and Role in Bone Health

Calcium is important for bone health as it plays a crucial role in building and maintaining strong bones. It is also essential for bone density and reducing the risk of fractures and osteoporosis, especially in older adults. In addition to this, calcium helps in the regulation of muscle contractions, including the heartbeat, and it is essential for the proper functioning of the nervous system.

Recent Research and Findings

Recent research has shown that calcium may have other health benefits beyond bone health. Some studies suggest that calcium may help lower blood pressure, reduce the risk of colorectal cancer, and improve weight loss in individuals following a calorie-restricted diet. However, more research is needed to confirm these findings and determine the optimal intake of calcium for these health benefits.

One study published in the Journal of the American College of Cardiology found that calcium supplementation was associated with a lower risk of heart disease in women. Another study published in the American Journal of Clinical Nutrition found that calcium supplementation improved insulin sensitivity and reduced inflammation in overweight and obese adults.

Symptoms of Deficiency

Calcium deficiency can lead to various health problems, including osteoporosis, weakened bones, and fractures. In children, it can also lead to delayed growth and development. Other symptoms of calcium deficiency include muscle cramps, tingling in the hands and feet, and irregular heartbeat.

Conclusion

Calcium is an essential mineral that is important for various bodily functions, especially bone health. Consuming a diet rich in calcium from various food sources is essential to maintain optimal health. Further research is needed to confirm the potential health benefits of calcium beyond bone health and determine the optimal intake for these benefits.

REFERENCES

  • National Institutes of Health. Calcium. https://ods.od.nih.gov/factsheets/Calcium-HealthProfessional/. Accessed May 9, 2023.
  • Buendia JR, Li Y, Hu FB, et al. Regular yogurt intake and risk of cardiovascular disease among hypertensive adults. J Am Coll Cardiol. 2018;71(21):2329-2337.
  • Major GC, Alarie FP, Dore J, et al. Supplementation with calcium, vitamin D, or both and weight loss in women. Am J Clin Nutr. 2008;88(4):906-912.
  • Weaver CM, Alexander DD, et al. Calcium plus vitamin D supplementation and risk of fractures: an updated meta-analysis from the National Osteoporosis Foundation. Osteoporos Int. 2016;27(1):367-376.
  • Bonjour JP, Kraenzlin M, et al. The effects of vitamin D supplementation on skeletal, vascular, or cancer outcomes: a trial sequential meta-analysis. Lancet Diabetes Endocrinol. 2021;9(2):75-87.
  • Lanham-New SA, et al. Vitamin D and SARS-CoV-2 virus/COVID-19 disease. BMJ Nutrition, Prevention & Health. 2020;3(1): doi: 10.1136/bmjnph-2020-000089.
  • Shams-White MM, Chung M, et al. Dietary protein and bone health: a systematic review and meta-analysis from the National Osteoporosis Foundation. Am J Clin Nutr. 2017;105(6):1528-1543.
  • Mangano KM, Walsh SJ, Insogna KL, Kenny AM, Kerstetter JE. Calcium intake in the United States from dietary and supplemental sources across adult age groups: new estimates from the National Health and Nutrition Examination Survey 2003-2006. J Am Diet Assoc. 2011;111(5):687-695.