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Written By THT Editorial Team
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Reviewed by Liza Nagarkoti , BSc Nursing, MA(Nutrition), Project Officer (Health) LWF Nepal
Vaccinations and immunizations play a crucial role in safeguarding the health of children by protecting them against various infectious diseases. This article explores common vaccinations recommended for children, their benefits, potential side effects, and interactions with other drugs based on recent research findings. Understanding the importance of vaccines and their potential risks is essential for making informed decisions about children’s healthcare.
Measles, Mumps, and Rubella (MMR) Vaccine: The MMR vaccine is typically administered in two doses, the first around 12 to 15 months of age and the second between 4 to 6 years. It provides protection against measles, mumps, and rubella. Research has shown that the MMR vaccine is highly effective in preventing these diseases and their associated complications (1). The most common side effects are mild and include fever and rash. It is essential to note that the MMR vaccine is not associated with an increased risk of autism (2).
Diphtheria, Tetanus, and Pertussis (DTaP) Vaccine: The DTaP vaccine is usually given in a series of five doses, with the first three doses administered at 2, 4, and 6 months of age, followed by boosters at 15 to 18 months and 4 to 6 years. This vaccine protects against diphtheria, tetanus, and pertussis (whooping cough). Research has demonstrated the effectiveness of the DTaP vaccine in preventing these diseases (3). Common side effects include redness, swelling, or tenderness at the injection site, as well as fever and fussiness.
Polio Vaccine: The polio vaccine is typically administered in a series of four doses, with the first three doses given at 2, 4, and 6 to 18 months of age, followed by a booster dose between 4 and 6 years. The vaccine protects against polio, a highly contagious viral infection. Research has shown that the polio vaccine has effectively reduced the global incidence of polio (4). Side effects are generally mild and include soreness or redness at the injection site.
Haemophilus influenzae type b (Hib) Vaccine: The Hib vaccine is administered in a series of three or four doses, with the first dose given at 2 months of age, followed by subsequent doses at 4 and 6 months. An additional dose may be given at 12 to 15 months, depending on the vaccine brand used. The Hib vaccine protects against Haemophilus influenzae type b, which can cause serious infections, including meningitis and pneumonia. Research has demonstrated the effectiveness of the Hib vaccine in preventing these diseases (5). Side effects are generally mild, with redness, swelling, or tenderness at the injection site being the most common.
Hepatitis B Vaccine: The hepatitis B vaccine is typically administered in a series of three doses, with the first dose given at birth, followed by subsequent doses at 1 to 2 months and 6 to 18 months of age. The vaccine protects against hepatitis B, a viral infection that can cause liver damage. Research has shown the effectiveness of the hepatitis B vaccine in preventing hepatitis B infection (6). Side effects are generally mild and include soreness or redness at the injection site.
Conclusion: Vaccinations and immunizations are vital for protecting children from preventable infectious diseases. The MMR, DT aP, polio, Hib, and hepatitis B vaccines are recommended for children at specific ages to provide protection against measles, mumps, rubella, diphtheria, tetanus, pertussis, polio, Haemophilus influenzae type b, and hepatitis B. Research has consistently shown the effectiveness of these vaccines in preventing the associated diseases and their complications. While mild side effects such as fever, redness, or tenderness at the injection site may occur, the benefits of vaccination outweigh the risks. It is important to consult healthcare professionals for personalized advice and to address any concerns regarding potential interactions with other medications.
REFERENCES
- MMR Vaccines: WHO position paper, April 2017. Weekly Epidemiological Record, 92(16), 205-228.
- Madsen, K. M., Hviid, A., Vestergaard, M., Schendel, D., Wohlfahrt, J., Thorsen, P., … & Melbye, M. (2002). A population-based study of measles, mumps, and rubella vaccination and autism. New England Journal of Medicine, 347(19), 1477- 1482.
- Kowalzik, F., Barbosa, A. P., Fernandes, V. R. F., & Battersby, A. (2020). A cell- mediated immunity pilot study of the fifth consecutive acellular pertussis booster vaccination in 4 to 6-year-old children: effects of a reduced antigenic load on the vaccine response. BMC Pediatrics, 20(1), 1-9.
- Immunization coverage. World Health Organization. Retrieved from https://www.who.int/news-room/fact-sheets/detail/immunization-coverage
- de Oliveira, L. H., Camacho, L. A., Coutinho, E. S., Martinez-Silveira, M. S., Carvalho, A. F., Ruiz-Matus, C., … & Andrus, J. K. (2015). Impact and effectiveness of Haemophilus influenzae type b conjugate vaccination in children and adults. Revista Panamericana de Salud Pública, 37(3), 147-154.
- Zanetti, A. R., Van Damme, P., Shouval, D., Van Herck, K., Van Der Meeren, O., Esteban, R., … & Hezode, C. (2008). The global impact of vaccination against hepatitis B: A historical overview. Vaccine, 26(49), 6266-6273.